Tracrium and Cefazolin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tracrium (atracurium besylate) and Cefazolin (cefazolin sodium). Common drug interactions include anaphylactoid reaction among females and hypotension among males.

The phase IV clinical study analyzes what interactions people have when they take Tracrium and Cefazolin. It is created by eHealthMe based on reports of 91 people who take the same drugs from the FDA, and is updated regularly.

What is Tracrium?

Tracrium has active ingredients of atracurium besylate. eHealthMe is studying from 909 Tracrium users. Check the latest studies of Tracrium.

What is Cefazolin?

Cefazolin has active ingredients of cefazolin sodium. It is often used in infection. eHealthMe is studying from 15,157 Cefazolin users. Check the latest studies of Cefazolin.

On Jul, 26, 2026

91 people who take Tracrium and Cefazolin together, and have interactions are studied.

Tracrium and Cefazolin drug interactions.

What are the common drug interactions of Tracrium and Cefazolin, by gender? *:

female:

Anaphylactoid reaction (type of anaphylaxis that does not involve an allergic reaction but is due to direct mast cell degranulation)
Blood culture positive
Device dislocation
Drug hypersensitivity
Gangrene (body tissue dies)
Genital disorder female (diseases of female genital tract)
Genital ulceration (ulcers on sex organ)
Haematoma (collection of blood outside the blood vessels)
Haemoglobin decreased
Leukopenia (less number of white blood cells in blood)

male:

Hypotension (abnormally low blood pressure)
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Erythema (redness of the skin)
Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
Hepatitis fulminant (life-threatening condition defined by significantly impaired liver function)
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Pruritus (severe itching of the skin)
Rash
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Apnoea (suspension of external breathing)

What are the common drug interactions of Tracrium and Cefazolin, by age (0-1 to 60+)? *:

0-1:

Prothrombin level decreased
Transaminases increased

2-9:

n/a

10-19:

n/a

20-29:

Acne (skin problems that cause pimples)
Asthenia (weakness)
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Coagulopathy (blood's ability to clot is impaired)
Drug hypersensitivity
Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
Hepatitis fulminant (life-threatening condition defined by significantly impaired liver function)
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Pruritus (severe itching of the skin)
Pruritus generalised (generalized itching)

30-39:

Grand mal convulsion (a type of generalized seizure that affects the entire brain)
Liver disorder (liver diseases)
Lung disorder (lung disease)
Rash papular (redness with papule)
Respiratory distress (difficulty in breathing)
Tonic clonic movements (generalized seizure that affects the entire brain)
Tremor (trembling or shaking movements in one or more parts of your body)
Renal failure acute (rapid kidney dysfunction)
Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Coagulopathy (blood's ability to clot is impaired)

40-49:

Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Erythema (redness of the skin)
Hypotension (abnormally low blood pressure)
Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
Anaphylactoid reaction (type of anaphylaxis that does not involve an allergic reaction but is due to direct mast cell degranulation)
Device dislocation
Medical device complication
Pancreatitis acute (sudden inflammation of pancreas)
Rash
Wheezing (a high-pitched whistling sound made while you breath)

50-59:

Hypotension (abnormally low blood pressure)
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Bradycardia (abnormally slow heart action)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Ventricular fibrillation (abnormally irregular heart rhythm)
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Generalised erythema (redness of the skin all over the body)
Blood pressure decreased
Cardiac arrest
Cardiogenic shock (inadequate circulation of blood)

60+:

Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Hypotension (abnormally low blood pressure)
Mouth ulceration (mouth ulcers)
Mucosal erosion (peeling off of mucous membrane)
Oral mucosal eruption (a sudden appearing of rash on mucous membrane of mouth)
Pruritus (severe itching of the skin)
Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Toxic skin eruption (skin breakdown due to toxic substance)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)

What are the existing conditions these people have? *

Anaesthesia: 30 people, 32.97%
General Anaesthesia: 28 people, 30.77%
Nausea (feeling of having an urge to vomit): 7 people, 7.69%
Pain: 6 people, 6.59%

* Approximation only. Some reports may have incomplete information.

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