Tradjenta and Jakafi drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tradjenta (linagliptin) and Jakafi (ruxolitinib phosphate). Common drug interactions include alopecia among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Tradjenta and Jakafi. It is created by eHealthMe based on reports of 87 people who take the same drugs from the FDA, and is updated regularly.

What is Tradjenta?

Tradjenta has active ingredients of linagliptin. It is often used in diabetes. eHealthMe is studying from 9,987 Tradjenta users. Check the latest studies of Tradjenta.

What is Jakafi?

Jakafi has active ingredients of ruxolitinib phosphate. It is often used in primary myelofibrosis. eHealthMe is studying from 56,530 Jakafi users. Check the latest studies of Jakafi.

On Jul, 09, 2026

87 people who take Tradjenta and Jakafi together, and have interactions are studied.

What are the common drug interactions of Tradjenta and Jakafi, by gender? *:

female:

Alopecia (absence of hair from areas of the body)
Diarrhoea
Epistaxis (bleed from the nose)
Headache (pain in head)
Influenza
Malaise (a feeling of general discomfort or uneasiness)
Parosmia (distortion of the sense of smell, as in smelling odours that are not present)
Sputum discoloured
Vomiting
Anaemia (lack of blood)

male:

Chronic kidney disease
Haemoglobin decreased
Rash
Skin cancer
Visual impairment
Vomiting
White blood cell count increased
Skin disorder (skin disease)
Dyspnoea (difficult or laboured respiration)
Malaise (a feeling of general discomfort or uneasiness)

What are the common drug interactions of Tradjenta and Jakafi, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Chronic kidney disease
Haemoglobin decreased
Pruritus (severe itching of the skin)
Rash
Skin cancer
Visual impairment
White blood cell count increased
Skin disorder (skin disease)
Dyspnoea (difficult or laboured respiration)
Malaise (a feeling of general discomfort or uneasiness)

What are the existing conditions these people have? *

Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 33 people, 37.93%
Type 2 Diabetes: 14 people, 16.09%
High Blood Pressure: 11 people, 12.64%
Pain: 10 people, 11.49%
Upper Respiratory Tract Infection: 8 people, 9.20%
Blood Uric Acid Increased: 8 people, 9.20%
Sinusitis (inflammation of sinus): 6 people, 6.90%
Rosacea (a skin condition that causes facial redness): 6 people, 6.90%
Restless Leg Syndrome (a powerful urge to move your legs): 6 people, 6.90%
Ocular Rosacea (redness, irritation or burning of the eyes): 6 people, 6.90%

* Approximation only. Some reports may have incomplete information.

Do you take Tradjenta and Jakafi?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously