Tramadol and Adderall 10 drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tramadol (tramadol hydrochloride) and Adderall 10 (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate). Common drug interactions include loss of consciousness among females and affect lability among males.

The phase IV clinical study analyzes what interactions people have when they take Tramadol and Adderall 10. It is created by eHealthMe based on reports of 43 people who take the same drugs from the FDA, and is updated regularly.

What is Tramadol?

Tramadol has active ingredients of tramadol hydrochloride. It is often used in pain. eHealthMe is studying from 235,798 Tramadol users. Check the latest studies of Tramadol.

What is Adderall 10?

Adderall 10 has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 5,182 Adderall 10 users. Check the latest studies of Adderall 10.

On Jul, 07, 2026

43 people who take Tramadol and Adderall 10 together, and have interactions are studied.

Tramadol and Adderall 10 drug interactions.

What are the common drug interactions of Tramadol and Adderall 10, by gender? *:

female:

Loss of consciousness
Memory impairment
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Mitral valve prolapse (heart's mitral valve doesn't work well)
Muscle atrophy (a decrease in the mass of the muscle)
Muscular weakness (muscle weakness)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Nicotine dependence
Oropharyngeal pain
Personality change

male:

Affect lability (emotional incontinence)
Anxiety
Insomnia (sleeplessness)
Libido decreased (loss of interest in sex)
Loss of employment
Memory impairment
Migraine (headache)
Muscle twitching
Nausea (feeling of having an urge to vomit)
Nervousness

What are the common drug interactions of Tramadol and Adderall 10, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Nausea (feeling of having an urge to vomit)
Abdominal pain upper
Agitation (state of anxiety or nervous excitement)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Fatigue (feeling of tiredness)
Gallbladder injury
Hypersomnia (excessive daytime sleepiness (eds))
Hypoaesthesia (reduced sense of touch or sensation)
Infectious mononucleosis (infection usually caused by the epstein-barr virus)
Lethargy (tiredness)

20-29:

Gallbladder disorder
Nausea (feeling of having an urge to vomit)
Abdominal discomfort
Cholecystitis chronic (long lasting infection of gallbladder)
Gallbladder injury
Abdominal pain upper
Anxiety
Bile duct stone
Cholecystitis (infection of gallbladder)
Deformity (disfigurement)

30-39:

Hypoaesthesia (reduced sense of touch or sensation)
Bone marrow disorder
Livedo reticularis (a lace-like purplish discoloration of the skin)
Migraine (headache)
Pain in extremity
Chest pain
Choking sensation (feeling of obstruction in respiratory system)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dyspnoea (difficult or laboured respiration)
Intervertebral disc degeneration (spinal disc degeneration)

40-49:

Headache (pain in head)
Blood cholesterol increased
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Chest discomfort
Diarrhoea
Disturbance in attention
Dyspnoea (difficult or laboured respiration)
Erythema (redness of the skin)
Fatigue (feeling of tiredness)
Hyperacusis (disorder in loudness perception)

50-59:

Chest discomfort
Erosive oesophagitis (acid reflux disease can cause tissue damage in the oesophagus over time)
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Dyspnoea (difficult or laboured respiration)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Hypoaesthesia (reduced sense of touch or sensation)
Muscle spasms (muscle contraction)
Muscle twitching
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)

60+:

Affect lability (emotional incontinence)
Anxiety
Breast cancer female
Excoriation (to tear or wear off the skin of)
Fall
Glioblastoma (most common and most aggressive malignant primary brain tumour in humans)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Rash

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 13.95%
Migraine (headache): 6 people, 13.95%
Depression: 6 people, 13.95%
Stress And Anxiety: 5 people, 11.63%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 11.63%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 5 people, 11.63%
Fatigue (feeling of tiredness): 5 people, 11.63%
Premenstrual Syndrome: 4 people, 9.30%
Neuralgia (pain in one or more nerves): 3 people, 6.98%
Insomnia (sleeplessness): 3 people, 6.98%

* Approximation only. Some reports may have incomplete information.

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