Tramadol and Minivelle drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tramadol (tramadol hydrochloride) and Minivelle (estradiol). Common drug interactions include headache among females and contusion among males.

The phase IV clinical study analyzes what interactions people have when they take Tramadol and Minivelle. It is created by eHealthMe based on reports of 56 people who take the same drugs from the FDA, and is updated regularly.

What is Tramadol?

Tramadol has active ingredients of tramadol hydrochloride. It is often used in pain. eHealthMe is studying from 235,798 Tramadol users. Check the latest studies of Tramadol.

What is Minivelle?

Minivelle has active ingredients of estradiol. eHealthMe is studying from 3,480 Minivelle users. Check the latest studies of Minivelle.

On Jul, 26, 2026

56 people who take Tramadol and Minivelle together, and have interactions are studied.

Tramadol and Minivelle drug interactions.

What are the common drug interactions of Tramadol and Minivelle, by gender? *:

female:

Headache (pain in head)
Muscle spasms (muscle contraction)
Spinal disorder (disease of spine a back bone)
Thrombosis (formation of a blood clot inside a blood vessel)
Asthma
Dyspnoea (difficult or laboured respiration)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Spondylitis (an inflammation of the vertebra with spinal cord involvement)
Weight increased
Blood pressure fluctuation

male:

Contusion (a type of hematoma of tissue in which capillaries)

What are the common drug interactions of Tramadol and Minivelle, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Migraine (headache)
Nausea (feeling of having an urge to vomit)
Fatigue (feeling of tiredness)
Intervertebral disc protrusion (spinal disc protrusion)
Blood pressure fluctuation
Blood pressure increased
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Nasopharyngitis (inflammation of the nasopharynx)
Spondylitis (an inflammation of the vertebra with spinal cord involvement)
Alopecia (absence of hair from areas of the body)

50-59:

Surgery
Weight decreased
Blood pressure increased
Cellulitis (infection under the skin)
Decreased appetite
Diarrhoea
Fall
Food allergy
Gallbladder disorder
Glossodynia (a burning or painful sensation in the tongue)

60+:

Drug ineffective
Fall
Head injury
Injury
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Urinary tract infection

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 32 people, 57.14%
Immunodeficiency Common Variable: 6 people, 10.71%
Migraine (headache): 5 people, 8.93%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 8.93%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 5.36%
Muscle Spasms (muscle contraction): 3 people, 5.36%

* Approximation only. Some reports may have incomplete information.

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