Tramadol and Mitigare drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tramadol (tramadol hydrochloride) and Mitigare (colchicine). Common drug interactions include chronic kidney disease among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Tramadol and Mitigare. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Tramadol?

Tramadol has active ingredients of tramadol hydrochloride. It is often used in pain. eHealthMe is studying from 235,798 Tramadol users. Check the latest studies of Tramadol.

What is Mitigare?

Mitigare has active ingredients of colchicine. eHealthMe is studying from 283 Mitigare users. Check the latest studies of Mitigare.



On Jul, 07, 2026

15 people who take Tramadol and Mitigare together, and have interactions are studied.

Tramadol and Mitigare drug interactions.

What are the common drug interactions of Tramadol and Mitigare, by gender? *:

female:

  1. Chronic kidney disease
  2. Acne (skin problems that cause pimples)
  3. Blood glucose fluctuation
  4. Blood glucose increased
  5. Hordeolum (small collection of pus (abscess) on the eyelid)
  6. Hypotension (abnormally low blood pressure)
  7. Migraine (headache)
  8. Urinary tract infection
  9. Arthralgia (joint pain)
  10. Breast cancer

male:

  1. Chronic kidney disease
  2. Emotional distress
  3. Periodontitis (inflammation of the tissue around the teeth)
  4. Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
  5. Hypertension (high blood pressure)
  6. Acute sinusitis
  7. Blood creatinine increased
  8. Bone density decreased
  9. Death
  10. Gait disturbance

What are the common drug interactions of Tramadol and Mitigare, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)

50-59:

  1. Acne (skin problems that cause pimples)
  2. Blood glucose fluctuation
  3. Blood glucose increased
  4. Emotional distress
  5. Hordeolum (small collection of pus (abscess) on the eyelid)
  6. Hypertension (high blood pressure)
  7. Migraine (headache)
  8. Arthralgia (joint pain)
  9. Blood creatinine increased
  10. Bone density decreased

60+:

  1. Hypotension (abnormally low blood pressure)
  2. Urinary tract infection
  3. Acute sinusitis
  4. Death
  5. Drug hypersensitivity
  6. Hospitalisation
  7. Hyperglycaemia (high blood sugar)
  8. Periodontitis (inflammation of the tissue around the teeth)
  9. Type 2 diabetes mellitus

What are the existing conditions these people have? *

  1. High Blood Cholesterol: 5 people, 33.33%
  2. Cardiac Failure: 5 people, 33.33%
  3. Gout (uric acid crystals building up in the body): 5 people, 33.33%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 33.33%
  5. Depression: 4 people, 26.67%
  6. Diabetes: 3 people, 20.00%
  7. Muscle Spasms (muscle contraction): 3 people, 20.00%
  8. Thyroid Diseases: 3 people, 20.00%
  9. Blood Pressure Abnormal: 3 people, 20.00%
  10. Kidney Stones: 3 people, 20.00%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Tramadol and Mitigare:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tramadol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Mitigare:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tramadol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Mitigare and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on tramadol hydrochloride and colchicine (the active ingredients of Tramadol and Mitigare, respectively), and Tramadol and Mitigare (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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