Trandate and Vytorin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trandate (labetalol hydrochloride) and Vytorin (ezetimibe; simvastatin). Common drug interactions include neutropenia among females and flushing among males.

The phase IV clinical study analyzes what interactions people have when they take Trandate and Vytorin. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Trandate?

Trandate has active ingredients of labetalol hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 1,735 Trandate users. Check the latest studies of Trandate.

What is Vytorin?

Vytorin has active ingredients of ezetimibe; simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 20,084 Vytorin users. Check the latest studies of Vytorin.

On Jul, 13, 2026

13 people who take Trandate and Vytorin together, and have interactions are studied.

What are the common drug interactions of Trandate and Vytorin, by gender? *:

female:

Neutropenia (an abnormally low number of neutrophils)
Cough
Thrombocytopenia (decrease of platelets in blood)
Anaemia (lack of blood)
Haematotoxicity (toxins that destroy red blood cells)
Spinal disorder (disease of spine a back bone)
Vaginal infection
Productive cough
Chronic kidney disease
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

male:

Flushing (the warm, red condition of human skin)
Pruritus (severe itching of the skin)
Hypersensitivity
Lethargy (tiredness)
Muscular weakness (muscle weakness)
Nausea (feeling of having an urge to vomit)
Nephrogenic anaemia (anaemia due to kidney disease)
Pulmonary congestion (congestion in the lungs)
Renal failure (kidney dysfunction)
Renal oncocytoma (a tumour of the kidney made up of oncocytes, a special kind of cell)

What are the common drug interactions of Trandate and Vytorin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Anxiety
Blood glucose increased
Cardiomegaly (increased size of heart than normal)
Dizziness
Dyspnoea (difficult or laboured respiration)
Electrocardiogram qt prolonged
Haemoglobin decreased
Hypersensitivity
Lethargy (tiredness)
Muscular weakness (muscle weakness)

50-59:

Neutropenia (an abnormally low number of neutrophils)
Cough
Thrombocytopenia (decrease of platelets in blood)
Anaemia (lack of blood)
Haematotoxicity (toxins that destroy red blood cells)
Spinal disorder (disease of spine a back bone)
Vaginal infection
Productive cough
Chronic kidney disease
Renal failure (kidney dysfunction)

60+:

Application site rash
Blood pressure inadequately controlled
Chronic kidney disease
Fall
Gait disturbance
Nephrogenic anaemia (anaemia due to kidney disease)
Oedema peripheral (superficial swelling)
Renal failure (kidney dysfunction)
Renal oncocytoma (a tumour of the kidney made up of oncocytes, a special kind of cell)
Wrist fracture

What are the existing conditions these people have? *

Wound Complication: 5 people, 38.46%
Multiple Myeloma (cancer of the plasma cells): 5 people, 38.46%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 38.46%
Upper Respiratory Tract Infection: 5 people, 38.46%
Mouth Ulcers: 5 people, 38.46%
Insomnia (sleeplessness): 5 people, 38.46%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 15.38%
Sleep Disorder: 2 people, 15.38%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 15.38%
Pain: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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