Tranexamic acid and Cymbalta drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tranexamic acid (tranexamic acid) and Cymbalta (duloxetine hydrochloride). Common drug interactions include arthralgia among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Tranexamic acid and Cymbalta. It is created by eHealthMe based on reports of 51 people who take the same drugs from the FDA, and is updated regularly.

What is Tranexamic acid?

Tranexamic acid has active ingredients of tranexamic acid. It is often used in heavy or prolong menstrual bleeding. eHealthMe is studying from 8,687 Tranexamic acid users. Check the latest studies of Tranexamic acid.

What is Cymbalta?

Cymbalta has active ingredients of duloxetine hydrochloride. It is often used in depression. eHealthMe is studying from 154,973 Cymbalta users. Check the latest studies of Cymbalta.



On Jul, 06, 2026

51 people who take Tranexamic acid and Cymbalta together, and have interactions are studied.

Tranexamic acid and Cymbalta drug interactions.

What are the common drug interactions of Tranexamic Acid and Cymbalta, by gender? *:

female:

  1. Arthralgia (joint pain)
  2. Asthma
  3. Blood cholesterol increased
  4. Blood pressure increased
  5. Decreased appetite
  6. Cough
  7. Urinary tract infection
  8. Dizziness
  9. Insomnia (sleeplessness)
  10. Nausea (feeling of having an urge to vomit)

male:

  1. Abdominal pain
  2. Retinal haemorrhage (bleeding from retina)
  3. Lung disorder (lung disease)
  4. Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)
  5. Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  6. Nephrogenic anaemia (anaemia due to kidney disease)
  7. Pruritus (severe itching of the skin)
  8. Renal failure (kidney dysfunction)
  9. Rib fracture
  10. Road traffic accident

What are the common drug interactions of Tranexamic Acid and Cymbalta, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Angioedema (rapid swelling of the dermis)
  2. Aphthous ulcer (mouth ulcer)
  3. Back pain
  4. Bone pain
  5. Headache (pain in head)
  6. Kidney infection
  7. Migraine (headache)
  8. Nausea (feeling of having an urge to vomit)
  9. Oral discomfort (pain or irritation in mouth)
  10. Pain

30-39:

  1. Anaemia (lack of blood)
  2. Gastroenteritis (inflammation of stomach and intestine)
  3. Hordeolum (small collection of pus (abscess) on the eyelid)
  4. Insomnia (sleeplessness)
  5. Muscle spasms (muscle contraction)
  6. Upper respiratory tract inflammation
  7. Cholinergic syndrome (symptoms of increased cholinergic stimulation)
  8. Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
  9. Vomiting

40-49:

  1. Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
  2. Intentional self-injury
  3. Decreased appetite
  4. Hangover
  5. Localised infection (infection at the single location)
  6. Cough
  7. Pyrexia (fever)
  8. Urticaria (rash of round, red welts on the skin that itch intensely)
  9. Aphonia (inability to produce voice)
  10. Arthritis (form of joint disorder that involves inflammation of one or more joints)

50-59:

  1. Urinary tract infection
  2. Nausea (feeling of having an urge to vomit)
  3. Alanine aminotransferase increased
  4. Aspartate aminotransferase increased
  5. Burning sensation
  6. Dizziness
  7. Hypoaesthesia (reduced sense of touch or sensation)
  8. Ligament sprain (ligament stretched)
  9. Lymphocyte count decreased
  10. Post herpetic neuralgia (neuralgia caused by the varicella zoster virus)

60+:

  1. Cerebral infarction (less blood supply to brain resulting tissue damage)
  2. Abdominal pain
  3. Renal failure (kidney dysfunction)
  4. Tongue haemorrhage (bleeding from tongue)
  5. Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
  6. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  7. Retinal haemorrhage (bleeding from retina)
  8. Sepsis (a severe blood infection that can lead to organ failure and death)
  9. Hypophagia (reduced food intake)
  10. Chronic kidney disease

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 17.65%
  2. Pain: 8 people, 15.69%
  3. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 13.73%
  4. Diabetes: 6 people, 11.76%
  5. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 5 people, 9.80%
  6. Migraine (headache): 5 people, 9.80%
  7. Insomnia (sleeplessness): 5 people, 9.80%
  8. Secondary Progressive Multiple Sclerosis (a stage of ms which comes after relapsing remitting ms in many cases): 4 people, 7.84%
  9. Post Herpetic Neuralgia (neuralgia caused by the varicella zoster virus): 4 people, 7.84%
  10. Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 7.84%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Tranexamic acid and Cymbalta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tranexamic acid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cymbalta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tranexamic acid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cymbalta and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on tranexamic acid and duloxetine hydrochloride (the active ingredients of Tranexamic acid and Cymbalta, respectively), and Tranexamic acid and Cymbalta (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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