Tranexamic acid and Dilaudid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tranexamic acid (tranexamic acid) and Dilaudid (hydromorphone hydrochloride). Common drug interactions include wound secretion among females and rib fracture among males.

The phase IV clinical study analyzes what interactions people have when they take Tranexamic acid and Dilaudid. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Tranexamic acid?

Tranexamic acid has active ingredients of tranexamic acid. It is often used in heavy or prolong menstrual bleeding. eHealthMe is studying from 8,687 Tranexamic acid users. Check the latest studies of Tranexamic acid.

What is Dilaudid?

Dilaudid has active ingredients of hydromorphone hydrochloride. It is often used in pain. eHealthMe is studying from 96,466 Dilaudid users. Check the latest studies of Dilaudid.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 24, 2026

27 people who take Tranexamic acid and Dilaudid together, and have interactions are studied.

Tranexamic acid and Dilaudid drug interactions.

What are the common drug interactions of Tranexamic Acid and Dilaudid, by gender? *:

female:

  1. Wound secretion
  2. Abscess limb (limb infection)
  3. Cellulitis (infection under the skin)
  4. Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
  5. Perineal abscess
  6. Pyrexia (fever)
  7. Sepsis (a severe blood infection that can lead to organ failure and death)
  8. Septic shock (shock due to blood infection)
  9. Vaginal cellulitis (vaginal spreading skin infection)
  10. Vulval abscess

male:

  1. Rib fracture
  2. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  3. Post procedural complication
  4. Vocal cord paralysis
  5. Anxiety
  6. Depression
  7. Libido increased (increased sexual urge to have sex)
  8. Road traffic accident
  9. Therapeutic response decreased (less preventive response)
  10. Weight increased

What are the common drug interactions of Tranexamic Acid and Dilaudid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Wound secretion
  2. Pyrexia (fever)
  3. Anaemia postoperative
  4. Constipation
  5. Disease recurrence
  6. Haemothorax (collection of blood in the pleural space (the space between the lungs and the walls of the chest))
  7. Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
  8. Hypotension (abnormally low blood pressure)
  9. Hypoxia (low oxygen in tissues)
  10. Pleural effusion (water on the lungs)

20-29:

  1. Discomfort
  2. Erythema (redness of the skin)
  3. Livedo reticularis (a lace-like purplish discoloration of the skin)
  4. Urticaria (rash of round, red welts on the skin that itch intensely)

30-39:

  1. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  2. Increased upper airway secretion
  3. Oral candidiasis (fungal infection of mouth)
  4. Pneumonia
  5. Respiratory failure (inadequate gas exchange by the respiratory system)
  6. Rib fracture
  7. Sleep-related eating disorder (abnormal eating patterns during the night)
  8. Weight decreased
  9. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
  10. Laryngeal disorder (disease of larynx related to voice)

40-49:

  1. Chronic kidney disease
  2. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  3. Nephrogenic anaemia (anaemia due to kidney disease)
  4. Renal failure (kidney dysfunction)

50-59:

  1. Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
  2. Perineal abscess
  3. Sepsis (a severe blood infection that can lead to organ failure and death)
  4. Septic shock (shock due to blood infection)
  5. Vaginal cellulitis (vaginal spreading skin infection)
  6. Vulval abscess
  7. Vulval cellulitis (inflammation of skin around vagina)
  8. Drug effect delayed
  9. Genital abscess (build up of pus in genital)
  10. Pelvic abscess

60+:

  1. Chronic kidney disease
  2. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  3. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  4. Hypoaesthesia (reduced sense of touch or sensation)
  5. Left ventricular dysfunction
  6. Left ventricular failure (left ventricle fails to contract forcefully)
  7. Nephrogenic anaemia (anaemia due to kidney disease)
  8. Renal failure (kidney dysfunction)

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 33.33%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 9 people, 33.33%
  3. Procedural Pain: 4 people, 14.81%
  4. Anaesthesia: 4 people, 14.81%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 14.81%
  6. Hypotension (abnormally low blood pressure): 3 people, 11.11%
  7. Constipation: 3 people, 11.11%
  8. Headache (pain in head): 2 people, 7.41%
  9. Anaemia (lack of blood): 2 people, 7.41%
  10. Back Pain: 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Tranexamic acid and Dilaudid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tranexamic acid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Dilaudid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tranexamic acid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Dilaudid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on tranexamic acid and hydromorphone hydrochloride (the active ingredients of Tranexamic acid and Dilaudid, respectively), and Tranexamic acid and Dilaudid (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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