Tranxene and Bextra drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tranxene (clorazepate dipotassium) and Bextra (valdecoxib). Common drug interactions include abdominal pain among females and angina pectoris among males.

The phase IV clinical study analyzes what interactions people have when they take Tranxene and Bextra. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Tranxene?

Tranxene has active ingredients of clorazepate dipotassium. It is often used in stress and anxiety. eHealthMe is studying from 6,550 Tranxene users. Check the latest studies of Tranxene.

What is Bextra?

Bextra has active ingredients of valdecoxib. It is often used in pain. eHealthMe is studying from 20,994 Bextra users. Check the latest studies of Bextra.

On Jul, 12, 2026

11 people who take Tranxene and Bextra together, and have interactions are studied.

What are the common drug interactions of Tranxene and Bextra, by gender? *:

female:

Abdominal pain
Hepatic adenoma (benign liver tumour)
Hypovolaemic shock (shock caused by severe blood or fluid loss)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Cholecystitis chronic (long lasting infection of gallbladder)
Diarrhoea
Dystonia (abnormal muscle tone)
Hepatic rupture (rapture of common benign tumour of liver)
Joint stiffness
Oculogyration (the movement of the eyeball about the anteroposterior axis)

male:

Angina pectoris (chest pain due to ischemia of the heart muscle)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Meningitis viral (viral inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
Migraine (headache)
Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
Post-traumatic stress disorder
Renal cell carcinoma stage unspecified (kidney cancer in unknown stage)
Renal disorder (kidney disease)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Swelling

What are the common drug interactions of Tranxene and Bextra, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal pain
Hepatic adenoma (benign liver tumour)
Hypovolaemic shock (shock caused by severe blood or fluid loss)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Cholecystitis chronic (long lasting infection of gallbladder)
Hepatic rupture (rapture of common benign tumour of liver)
Procedural pain
Tumour rupture (tear in tumour)
Atelectasis (partial or complete collapse of the lung)
Cholecystitis (infection of gallbladder)

30-39:

n/a

40-49:

Dizziness
Fatigue (feeling of tiredness)
Incoherent (talking in a confused and unclear way)
Tongue paralysis (loss of function of tongue)

50-59:

n/a

60+:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Diarrhoea
Tremor (trembling or shaking movements in one or more parts of your body)
Trismus (reduced opening of the jaws)
Weight decreased
Angina pectoris (chest pain due to ischemia of the heart muscle)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Blood cholesterol increased
Bruxism (habitual grinding of the teeth, typically during sleep)

What are the existing conditions these people have? *

Birth Control: 3 people, 27.27%
Acne (skin problems that cause pimples): 3 people, 27.27%
Irritable Bowel Syndrome: 2 people, 18.18%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 18.18%
Abdominal Pain: 2 people, 18.18%
Rashes (redness): 1 person, 9.09%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 1 person, 9.09%
Oedema Peripheral (superficial swelling): 1 person, 9.09%
Migraine (headache): 1 person, 9.09%
Inflammation: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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