Treanda and Glucophage drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Treanda (bendamustine hydrochloride) and Glucophage (metformin hydrochloride). Common drug interactions include pyrexia among females and syncope among males.

The phase IV clinical study analyzes what interactions people have when they take Treanda and Glucophage. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Treanda?

Treanda has active ingredients of bendamustine hydrochloride. It is often used in non-hodgkin's lymphoma. eHealthMe is studying from 4,411 Treanda users. Check the latest studies of Treanda.

What is Glucophage?

Glucophage has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 60,851 Glucophage users. Check the latest studies of Glucophage.



On Jul, 13, 2026

13 people who take Treanda and Glucophage together, and have interactions are studied.

Treanda and Glucophage drug interactions.

What are the common drug interactions of Treanda and Glucophage, by gender? *:

female:

  1. Pyrexia (fever)
  2. Necrotising retinitis (life threatening infection of retina)
  3. Anaemia haemolytic autoimmune (a condition in which the immune system attacks the red blood cells, resulting in fewer of these oxygen-transporting cells)
  4. Chills (felling of cold)
  5. Confusional state
  6. Diarrhoea
  7. Disease progression
  8. Dyspnoea (difficult or laboured respiration)
  9. Hepatosplenomegaly (enlargement of both the liver and the spleen)
  10. Lymphadenopathy (disease or enlargement of lymph nodes)

male:

  1. Syncope (loss of consciousness with an inability to maintain postural tone)
  2. Thrombocytopenia (decrease of platelets in blood)
  3. Febrile neutropenia (fever with reduced white blood cells)
  4. Lung disorder (lung disease)
  5. Peripheral coldness
  6. Platelet count decreased
  7. Pulmonary embolism (blockage of the main artery of the lung)
  8. White blood cell count decreased

What are the common drug interactions of Treanda and Glucophage, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Hypoglycaemia (deficiency of glucose in the bloodstream)
  2. Infection
  3. Disease progression
  4. Dyspnoea (difficult or laboured respiration)
  5. Febrile neutropenia (fever with reduced white blood cells)
  6. Hepatosplenomegaly (enlargement of both the liver and the spleen)
  7. Lung disorder (lung disease)
  8. Lymphadenopathy (disease or enlargement of lymph nodes)
  9. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  10. Peripheral coldness

What are the existing conditions these people have? *

  1. Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 5 people, 38.46%
  2. High Blood Pressure: 5 people, 38.46%
  3. High Blood Cholesterol: 4 people, 30.77%
  4. Type 2 Diabetes: 3 people, 23.08%
  5. Multiple Myeloma (cancer of the plasma cells): 2 people, 15.38%
  6. Post Herpetic Neuralgia (neuralgia caused by the varicella zoster virus): 1 person, 7.69%
  7. Pneumocystis Jiroveci Pneumonia (fungal infection of the lungs): 1 person, 7.69%
  8. Insomnia (sleeplessness): 1 person, 7.69%
  9. Hypokalemia (low potassium): 1 person, 7.69%
  10. Herpes Zoster: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Treanda and Glucophage?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Treanda and Glucophage:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Treanda:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Glucophage:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Treanda and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Glucophage and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on bendamustine hydrochloride and metformin hydrochloride (the active ingredients of Treanda and Glucophage, respectively), and Treanda and Glucophage (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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