Treanda and Ondansetron drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Treanda (bendamustine hydrochloride) and Ondansetron (ondansetron). Common drug interactions include platelet count decreased among females and tumour lysis syndrome among males.
The phase IV clinical study analyzes what interactions people have when they take Treanda and Ondansetron. It is created by eHealthMe based on reports of 98 people who take the same drugs from the FDA, and is updated regularly.
What is Treanda?
Treanda has active ingredients of bendamustine hydrochloride. It is often used in non-hodgkin's lymphoma. eHealthMe is studying from 4,411 Treanda users. Check the latest studies of Treanda.
What is Ondansetron?
Ondansetron has active ingredients of ondansetron. It is often used in nausea. eHealthMe is studying from 122,738 Ondansetron users. Check the latest studies of Ondansetron.
98 people who take Treanda and Ondansetron together, and have interactions are studied.

What are the common drug interactions of Treanda and Ondansetron, by gender? *:
female:
- Platelet count decreased
- White blood cell count decreased
- Pyrexia (fever)
- Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
- Constipation
- Hypokalaemia (low potassium)
- Infusion site pain
- International normalised ratio increased
- Renal failure acute (rapid kidney dysfunction)
- Weight fluctuation
male:
- Tumour lysis syndrome (a group of metabolic complications that can occur after treatment of cancer, these complications are caused by the breakdown products of dying cancer cells)
- Diarrhoea
- Hyperkalaemia (damage to or disease of the kidney)
- Pyrexia (fever)
- Thrombocytopenia (decrease of platelets in blood)
- Hypotension (abnormally low blood pressure)
- Pleural effusion (water on the lungs)
- Renal tubular necrosis (death of kidney tubules)
- Skin toxicity (skin damage due to toxin/poison)
- Toxic skin eruption (skin breakdown due to toxic substance)
What are the common drug interactions of Treanda and Ondansetron, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Renal impairment (severely reduced kidney function)
20-29:
- Pyelonephritis (inflammation of kidney caused by bacteria)
30-39:
n/a
40-49:
- Constipation
- Infusion site haematoma (localized swelling filled with blood at infusion site)
- Infusion site phlebitis (inflammation of the walls of a vein at infusion site)
- Infusion site reaction
- Urticaria (rash of round, red welts on the skin that itch intensely)
50-59:
- Ascites (accumulation of fluid in the abdominal cavity)
- Asthenia (weakness)
- Chills (felling of cold)
- Dehydration (dryness resulting from the removal of water)
- Dizziness
- Headache (pain in head)
- Hyperkalaemia (damage to or disease of the kidney)
- Infusion related reaction
- Neutropenia (an abnormally low number of neutrophils)
- Pleural effusion (water on the lungs)
60+:
- Hypotension (abnormally low blood pressure)
- Renal failure acute (rapid kidney dysfunction)
- Toxic skin eruption (skin breakdown due to toxic substance)
- Hypokalaemia (low potassium)
- Chills (felling of cold)
- Fatigue (feeling of tiredness)
- Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection)
- Lymphocyte count decreased
- Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
What are the existing conditions these people have? *
- Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 19 people, 19.39%
- Burkitt Lymphoma (cancer of the lymphatic system): 14 people, 14.29%
- Stress And Anxiety: 11 people, 11.22%
- High Blood Pressure: 11 people, 11.22%
- Pain: 10 people, 10.20%
- Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 7 people, 7.14%
- Insomnia (sleeplessness): 6 people, 6.12%
- Diarrhea: 5 people, 5.10%
- Constipation: 5 people, 5.10%
* Approximation only. Some reports may have incomplete information.
Do you take Treanda and Ondansetron?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Treanda (4,411 reports)
- Ondansetron (122,738 reports)
Browse all drug interactions of Treanda and Ondansetron:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Treanda:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Ondansetron:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Treanda and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ondansetron and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on bendamustine hydrochloride and ondansetron (the active ingredients of Treanda and Ondansetron, respectively), and Treanda and Ondansetron (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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