Treanda and Profen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Treanda (bendamustine hydrochloride) and Profen (ibuprofen). Common drug interactions include hypertension among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Treanda and Profen. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Treanda?

Treanda has active ingredients of bendamustine hydrochloride. It is often used in non-hodgkin's lymphoma. eHealthMe is studying from 4,411 Treanda users. Check the latest studies of Treanda.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,312 Profen users. Check the latest studies of Profen.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

27 people who take Treanda and Profen together, and have interactions are studied.

What are the common drug interactions of Treanda and Profen, by gender? *:

female:

Hypertension (high blood pressure)
Hypokalaemia (low potassium)
Osteoporosis (bones weak and more likely to break)
Spinal fracture (fracture in one of vertebrae)
Vitamin d deficiency
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Nocardiosis (an infectious disease affecting either the lungs or whole body)
Hypotension (abnormally low blood pressure)
Colitis (inflammation of colon)
Neutropenia (an abnormally low number of neutrophils)

male:

Pyrexia (fever)
Death
Asthenia (weakness)
Herpes simplex (herpes simplex is a common viral infection)
Rash pruritic (redness with itching)
Urticaria (rash of round, red welts on the skin that itch intensely)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Aplasia (defective development or congenital absence of an organ or tissue)
Arthralgia (joint pain)

What are the common drug interactions of Treanda and Profen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Pyrexia (fever)
Death
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)

50-59:

Pneumonia
Neutropenia (an abnormally low number of neutrophils)
Rash erythematous (redness of the skin)

60+:

Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
General physical health deterioration (weak health status)
Asthenia (weakness)
Colitis (inflammation of colon)
Herpes simplex (herpes simplex is a common viral infection)
Rash pruritic (redness with itching)
Urticaria (rash of round, red welts on the skin that itch intensely)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Aplasia (defective development or congenital absence of an organ or tissue)

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 6 people, 22.22%
Diarrhea: 4 people, 14.81%
Insomnia (sleeplessness): 3 people, 11.11%
Pain In Extremity: 3 people, 11.11%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 3 people, 11.11%
Depression: 3 people, 11.11%
Cough: 3 people, 11.11%
Multiple Myeloma (cancer of the plasma cells): 3 people, 11.11%
Burkitt Lymphoma (cancer of the lymphatic system): 3 people, 11.11%
Infection: 3 people, 11.11%

* Approximation only. Some reports may have incomplete information.

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