Trental and Captopril drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trental (pentoxifylline) and Captopril (captopril). Common drug interactions include renal failure among females and myocardial infarction among males.

The phase IV clinical study analyzes what interactions people have when they take Trental and Captopril. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Trental?

Trental has active ingredients of pentoxifylline. eHealthMe is studying from 3,511 Trental users. Check the latest studies of Trental.

What is Captopril?

Captopril has active ingredients of captopril. It is often used in high blood pressure. eHealthMe is studying from 17,438 Captopril users. Check the latest studies of Captopril.

On Aug, 13, 2026

22 people who take Trental and Captopril together, and have interactions are studied.

Trental and Captopril drug interactions.

What are the common drug interactions of Trental and Captopril, by gender? *:

female:

Renal failure (kidney dysfunction)
Blood creatinine increased
Brain injury
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Blood lactate dehydrogenase increased
Blood urea increased
Pneumonia
Pruritus (severe itching of the skin)
Activated partial thromboplastin time prolonged

male:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Cholecystitis chronic (long lasting infection of gallbladder)
Diabetes mellitus inadequate control
Listless (lack of interest, energy, or spirit)
Muscle twitching
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pneumonia
Abdominal pain upper
Amputation
Anaemia (lack of blood)

What are the common drug interactions of Trental and Captopril, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Renal failure (kidney dysfunction)
Brain injury
Cholecystitis chronic (long lasting infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Diabetic nephropathy (diabetic kidney disease)
Glomerulonephritis proliferative (a disorder of the glomeruli (glomerulonephritis), or small blood vessels in the kidneys)
Hyperkalaemia (damage to or disease of the kidney)
Nephritis interstitial (a kidney condition characterized by swelling in between the kidney tubules)
Prostatic abscess (a closed pocket containing pus within the prostate)
Renal failure acute (rapid kidney dysfunction)

60+:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Pneumonia
Pruritus (severe itching of the skin)
Abdominal pain upper
Activated partial thromboplastin time prolonged
Amputation
Anaemia (lack of blood)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Blood fibrinogen increased
Blood lactate dehydrogenase increased

What are the existing conditions these people have? *

Systemic Sclerosis (Scleroderma) (an autoimmune or connective tissue disease. it is characterized by thickening of the skin): 3 people, 13.64%
Sleep Disorder: 3 people, 13.64%
Infection: 3 people, 13.64%
Heart Disease: 3 people, 13.64%
Fever: 3 people, 13.64%
Constipation: 3 people, 13.64%
Arrhythmias (irregular heartbeat): 3 people, 13.64%
Anaemia (lack of blood): 3 people, 13.64%
Acute Kidney Failure: 3 people, 13.64%
Type 2 Diabetes: 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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