Treprostinil and Zoloft drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Treprostinil (treprostinil) and Zoloft (sertraline hydrochloride). Common drug interactions include headache among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Treprostinil and Zoloft. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Treprostinil?

Treprostinil has active ingredients of treprostinil. eHealthMe is studying from 7,695 Treprostinil users. Check the latest studies of Treprostinil.

What is Zoloft?

Zoloft has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 138,798 Zoloft users. Check the latest studies of Zoloft.

On Jul, 07, 2026

18 people who take Treprostinil and Zoloft together, and have interactions are studied.

Treprostinil and Zoloft drug interactions.

What are the common drug interactions of Treprostinil and Zoloft, by gender? *:

female:

Headache (pain in head)
Insomnia (sleeplessness)
Oxygen saturation decreased
Productive cough
Malaise (a feeling of general discomfort or uneasiness)
Chest pain
Cough
Dyspnoea (difficult or laboured respiration)
Fluid retention (an abnormal accumulation of fluid in the blood)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)

male:

Abdominal pain
Faecaloma (hard mass of fecal matter)
Respiratory tract infection
Blood pressure decreased
Acute respiratory failure
Asthenia (weakness)
Bronchial secretion retention
Colostomy
Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
Impaired healing

What are the common drug interactions of Treprostinil and Zoloft, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abdominal pain
Faecaloma (hard mass of fecal matter)

20-29:

n/a

30-39:

Anorectal discomfort
Catheter site infection (infection at the site of insertion)
Dry skin
Erythema (redness of the skin)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Hypercalcaemia (elevated calcium (ca+) level in the blood)
Hypokalaemia (low potassium)
Kidney infection
Migraine (headache)
Nausea (feeling of having an urge to vomit)

40-49:

Viral infection

50-59:

Dehydration (dryness resulting from the removal of water)
Diarrhoea
Nausea (feeling of having an urge to vomit)
Urinary tract infection enterococcal
Vomiting
Acute respiratory failure
Asthenia (weakness)
Bronchial secretion retention
Chest pain
Colostomy

60+:

Insomnia (sleeplessness)
Oxygen saturation decreased
Chest pain
Decreased appetite
Pain in jaw
Productive cough
Pulmonary thrombosis (scarring in the lungs)
Therapeutic response decreased (less preventive response)
Weight increased
Blood pressure decreased

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 15 people, 83.33%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 4 people, 22.22%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 5.56%
Abnormal Behavior: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

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