Tresiba and Adderall drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tresiba (insulin degludec) and Adderall (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate). Common drug interactions include blood glucose decreased among females and gastrooesophageal reflux disease among males.

The phase IV clinical study analyzes what interactions people have when they take Tresiba and Adderall. It is created by eHealthMe based on reports of 46 people who take the same drugs from the FDA, and is updated regularly.

What is Tresiba?

Tresiba has active ingredients of insulin degludec. It is often used in type 1 diabetes. eHealthMe is studying from 20,677 Tresiba users. Check the latest studies of Tresiba.

What is Adderall?

Adderall has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 64,224 Adderall users. Check the latest studies of Adderall.

On Jul, 16, 2026

46 people who take Tresiba and Adderall together, and have interactions are studied.

What are the common drug interactions of Tresiba and Adderall, by gender? *:

female:

Blood glucose decreased
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Nausea (feeling of having an urge to vomit)
Vomiting
Fatigue (feeling of tiredness)
Arthralgia (joint pain)
Headache (pain in head)
Agitation (state of anxiety or nervous excitement)
Anxiety
Arthropathy

male:

Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Neuropathy peripheral (surface nerve damage)
Death
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetic foot
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Hospitalisation
Nausea (feeling of having an urge to vomit)
Pancreatitis (inflammation of pancreas)
Shoulder operation

What are the common drug interactions of Tresiba and Adderall, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Nausea (feeling of having an urge to vomit)
Staphylococcal infection (an infection with staphylococcus bacteria)

30-39:

Death
Fatigue (feeling of tiredness)
Fungal infection
Ovarian cyst (fluid filled sac of the ovary)
Vaginal haemorrhage (vaginal bleeding)

40-49:

Suicidal ideation
Back pain
Fall
Anxiety
Cholesteatoma (abnormal skin growth in the middle ear behind the eardrum)
Chronic kidney disease
Constipation
Enteritis (inflammation of the small intestine)
Fatigue (feeling of tiredness)
Hospitalisation

50-59:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Vomiting
Adverse drug reaction
Bell's palsy (facial paralysis)
Bruxism (habitual grinding of the teeth, typically during sleep)
Endocarditis (inflammation in heart muscle)
Hypercalcaemia (elevated calcium (ca+) level in the blood)
Obstructive airways disorder (a progressive disease that makes it hard to breathe)
Ovarian cancer stage iii
Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands)

60+:

Abdominal discomfort
Abdominal pain
Retching (strong involuntary effort to vomit)
Stress
Arthralgia (joint pain)
Blood glucose decreased
Fatigue (feeling of tiredness)
Glycosylated haemoglobin increased
Irritability
Nausea (feeling of having an urge to vomit)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 20 people, 43.48%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 15 people, 32.61%
Drowsiness: 8 people, 17.39%
Diabetes: 8 people, 17.39%
Pain: 5 people, 10.87%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 10.87%
Depression: 5 people, 10.87%
Stress And Anxiety: 4 people, 8.70%
High Blood Pressure: 4 people, 8.70%
Nausea (feeling of having an urge to vomit): 3 people, 6.52%

* Approximation only. Some reports may have incomplete information.

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