Triazolam and Ultram drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Triazolam (triazolam) and Ultram (tramadol hydrochloride). Common drug interactions include post procedural complication among females and convulsion among males.

The phase IV clinical study analyzes what interactions people have when they take Triazolam and Ultram. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Triazolam?

Triazolam has active ingredients of triazolam. It is often used in insomnia. eHealthMe is studying from 5,838 Triazolam users. Check the latest studies of Triazolam.

What is Ultram?

Ultram has active ingredients of tramadol hydrochloride. It is often used in pain. eHealthMe is studying from 28,425 Ultram users. Check the latest studies of Ultram.



On Jul, 18, 2026

36 people who take Triazolam and Ultram together, and have interactions are studied.

Triazolam and Ultram drug interactions.

What are the common drug interactions of Triazolam and Ultram, by gender? *:

female:

  1. Post procedural complication
  2. Prothrombin level increased
  3. Pain in extremity
  4. Chest pain
  5. Drug ineffective
  6. Oedema peripheral (superficial swelling)
  7. Diarrhoea
  8. Abdominal pain upper
  9. Chills (felling of cold)
  10. Chondropathy (disease of the cartilage)

male:

  1. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  2. Influenza
  3. Asthma
  4. Drug toxicity
  5. Laryngotracheo bronchitis (inflammation of the larynx and trachea and bronchial passageways)
  6. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  7. Syncope (loss of consciousness with an inability to maintain postural tone)
  8. Arthralgia (joint pain)
  9. Hypoaesthesia (reduced sense of touch or sensation)
  10. Limb injury

What are the common drug interactions of Triazolam and Ultram, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
  2. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  3. Blood cholesterol increased
  4. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  5. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  6. Glaucoma (increased fluid pressure in the eye with vision loss)
  7. Hypertension (high blood pressure)
  8. Neuropathy peripheral (surface nerve damage)
  9. Purpura senile (skin condition in which areas of the skin develop a purplish or reddish-brown appearance due to bleeding of small blood vessels underneath)
  10. Renal failure (kidney dysfunction)

40-49:

  1. Sebaceous gland disorder (disease of oil gland of skin)
  2. Asthma
  3. Dependence
  4. Drug toxicity
  5. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  6. Chronic kidney disease
  7. Arthralgia (joint pain)
  8. Hypoaesthesia (reduced sense of touch or sensation)
  9. Limb injury
  10. Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)

50-59:

  1. Pain in extremity
  2. Abdominal pain upper
  3. Chest pain
  4. Chills (felling of cold)
  5. Chondropathy (disease of the cartilage)
  6. Decreased appetite
  7. Diarrhoea
  8. Drug ineffective
  9. Fall
  10. Feeling cold

60+:

  1. Chest pain
  2. Drug ineffective
  3. Feeling cold
  4. Formication (a sensation that exactly resembles that of small insects crawling on (or under) the skin)
  5. Gait disturbance
  6. Night sweats (sweating in night)
  7. Nodule (a growth of abnormal tissue)
  8. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  9. Poor quality sleep
  10. Pruritus (severe itching of the skin)

What are the existing conditions these people have? *

  1. Fibromyalgia (a long-term condition which causes pain all over the body): 11 people, 30.56%
  2. Joint Pain: 10 people, 27.78%
  3. Muscle Spasms (muscle contraction): 9 people, 25.00%
  4. Spinal Pain (pain in spine): 9 people, 25.00%
  5. High Blood Pressure: 9 people, 25.00%
  6. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 7 people, 19.44%
  7. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 7 people, 19.44%
  8. Spinal Disorder (disease of spine a back bone): 6 people, 16.67%
  9. Scoliosis (a medical condition in which a person's spine is curved from side to side): 6 people, 16.67%
  10. Intervertebral Disc Degeneration (spinal disc degeneration): 6 people, 16.67%

* Approximation only. Some reports may have incomplete information.

Do you take Triazolam and Ultram?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Triazolam and Ultram:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Triazolam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ultram:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Triazolam and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ultram and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on triazolam and tramadol hydrochloride (the active ingredients of Triazolam and Ultram, respectively), and Triazolam and Ultram (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: