Trileptal and Corlanor drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Trileptal (oxcarbazepine) and Corlanor (ivabradine hydrochloride). Common drug interactions include ankylosing spondylitis among females.
The phase IV clinical study analyzes what interactions people have when they take Trileptal and Corlanor. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.
What is Trileptal?
Trileptal has active ingredients of oxcarbazepine. It is often used in bipolar disorder. eHealthMe is studying from 23,558 Trileptal users. Check the latest studies of Trileptal.
What is Corlanor?
Corlanor has active ingredients of ivabradine hydrochloride. eHealthMe is studying from 2,453 Corlanor users. Check the latest studies of Corlanor.
16 people who take Trileptal and Corlanor together, and have interactions are studied.

What are the common drug interactions of Trileptal and Corlanor, by gender? *:
female:
- Ankylosing spondylitis (type of arthritis affecting the spine)
- Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
- Vitamin d deficiency
- Anaphylactic reaction (serious allergic reaction)
- Arrhythmia (irregular heartbeat)
- Back pain
- Death
- Drug hypersensitivity
- Dyspnoea (difficult or laboured respiration)
- Hypoglobulinaemia (deficiency of globulin in the bloodstream)
male:
n/a
What are the common drug interactions of Trileptal and Corlanor, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Sinusitis (inflammation of sinus)
- Ankylosing spondylitis (type of arthritis affecting the spine)
- Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
- Osteomalacia (softening of the bones due to a lack of vitamin d)
- Attention deficit hyperactivity disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness)
- Vitamin d deficiency
- Back pain
- Dyspnoea (difficult or laboured respiration)
- Hypotension (abnormally low blood pressure)
30-39:
n/a
40-49:
n/a
50-59:
- Anaphylactic reaction (serious allergic reaction)
- Syncope (loss of consciousness with an inability to maintain postural tone)
60+:
n/a
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 13 people, 81.25%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 8 people, 50.00%
- Drowsiness: 2 people, 12.50%
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 1 person, 6.25%
* Approximation only. Some reports may have incomplete information.
Do you take Trileptal and Corlanor?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Trileptal and Corlanor:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Trileptal:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Corlanor:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Trileptal and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Corlanor and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on oxcarbazepine and ivabradine hydrochloride (the active ingredients of Trileptal and Corlanor, respectively), and Trileptal and Corlanor (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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