Trileptal and Progesterone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trileptal (oxcarbazepine) and Progesterone (progesterone). Common drug interactions include dizziness among females and breech delivery among males.

The phase IV clinical study analyzes what interactions people have when they take Trileptal and Progesterone. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Trileptal?

Trileptal has active ingredients of oxcarbazepine. It is often used in bipolar disorder. eHealthMe is studying from 23,558 Trileptal users. Check the latest studies of Trileptal.

What is Progesterone?

Progesterone has active ingredients of progesterone. It is often used in menopause. eHealthMe is studying from 21,022 Progesterone users. Check the latest studies of Progesterone.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

35 people who take Trileptal and Progesterone together, and have interactions are studied.

Trileptal and Progesterone drug interactions.

What are the common drug interactions of Trileptal and Progesterone, by gender? *:

female:

Dizziness
Headache (pain in head)
Infection
Large intestine perforation (hole in large intestine)
Nausea (feeling of having an urge to vomit)
Weight decreased
Complex partial seizures (epileptic seizure)
Anaemia (lack of blood)
Depression
Dyskinesia (abnormality or impairment of voluntary movement)

male:

Breech delivery (delivery of an infant whose feet or buttocks appear first)
Neonatal disorder (disease of neonates)
Neonatal apnoeic attack (episodes where breathing stops temporarily in neonate)
Neonatal respiratory distress syndrome (a serious medical condition where a newborn baby's lungs cannot provide their body with enough oxygen)
Optic nerve disorder (disease of optic nerve)
Thrombocytopenia neonatal (decrease of platelets in blood in baby less than a month)
Premature baby
Cardiac murmur (an heart sound in valve abnormality)
Cerebral haemorrhage neonatal (bleeding in brain of baby of less than 1 month age)
Convulsion neonatal (muscle contraction and relaxation rapidly in neonate)

What are the common drug interactions of Trileptal and Progesterone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Asthenia (weakness)
Balance disorder
Constipation
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Depression
Drug toxicity
Fatigue (feeling of tiredness)
Lethargy (tiredness)
Nausea (feeling of having an urge to vomit)

20-29:

n/a

30-39:

Chest pain
Dyspnoea (difficult or laboured respiration)
Fluid retention (an abnormal accumulation of fluid in the blood)
Weight increased

40-49:

Dizziness
Dyskinesia (abnormality or impairment of voluntary movement)
Headache (pain in head)
Laryngitis (inflammation of the larynx)
Agitation (state of anxiety or nervous excitement)
Body temperature increased
Hyperglycaemia (high blood sugar)
Hyperphagia (an abnormal appetite for food)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Rash

50-59:

Infection
Large intestine perforation (hole in large intestine)
Abdominal pain
Crying
Depression
Dizziness
Dyspnoea (difficult or laboured respiration)
Flushing (the warm, red condition of human skin)
Headache (pain in head)
Injection site erythema (redness at injection site)

60+:

n/a

What are the existing conditions these people have? *

Fibromyalgia (a long-term condition which causes pain all over the body): 8 people, 22.86%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 6 people, 17.14%
Hypersensitivity: 5 people, 14.29%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 4 people, 11.43%
Stress And Anxiety: 3 people, 8.57%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 3 people, 8.57%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 8.57%
High Blood Pressure: 3 people, 8.57%
Hot Flush (sudden feelings of heat): 3 people, 8.57%
Hypoaesthesia (reduced sense of touch or sensation): 3 people, 8.57%

* Approximation only. Some reports may have incomplete information.

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