Apresoline and Glaucoma - a phase IV clinical study of FDA data

Summary:

Glaucoma is reported as a side effect among people who take Apresoline (hydralazine hydrochloride), especially for people who are female, 60+ old, also take Hydroxyurea, and have Depression.

The phase IV clinical study analyzes which people have Glaucoma when taking Apresoline. It is created by eHealthMe based on reports of 2,441 people who have side effects when taking Apresoline from the FDA, and is updated regularly.

What is Apresoline?

Apresoline has active ingredients of hydralazine hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 2,475 Apresoline users. Check the latest studies of Apresoline.

What is Glaucoma?

Glaucoma (increased fluid pressure in the eye with vision loss) is found to be associated with 1,233 drugs and 1,657 conditions by eHealthMe. Check the latest studies of Glaucoma.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

2,441 people reported to have side effects when taking Apresoline.
Among them, 19 people (0.78%) have Glaucoma.

Among these 19 people:

What is the gender of people who have Glaucoma when taking Apresoline? *

female: 100 %
male: 0.0 %

What is the age of people who have Glaucoma when taking Apresoline? *

What are other drugs people take besides Apresoline? *

What are other side effects people have besides Glaucoma? *

Vision Blurred: 16 people, 84.21%
Gallstones (stone formation by bile component): 16 people, 84.21%
Pneumonia: 14 people, 73.68%
Acute Kidney Failure: 13 people, 68.42%
Zollinger-Ellison Syndrome (increased production of the hormone gastrin from a small tumour of pancreas): 12 people, 63.16%
Fall: 12 people, 63.16%
Ectropion (lower eyelid turns outwards): 12 people, 63.16%
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 12 people, 63.16%
Enlarged Heart: 12 people, 63.16%
Extrasystoles: 12 people, 63.16%

What are the existing conditions these people have? *

Pain: 12 people, 63.16%
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 12 people, 63.16%
Depression: 12 people, 63.16%
Heart Disease: 4 people, 21.05%
Asthma: 4 people, 21.05%
Acromegaly (body produces too much growth hormone, leading to excess growth of body tissues): 4 people, 21.05%
Hyperthyroidism (over activity of the thyroid gland): 3 people, 15.79%
Ear Disorder: 2 people, 10.53%
Arrhythmias (irregular heartbeat): 2 people, 10.53%
Blood Pressure Abnormal: 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Apresoline and have Glaucoma?

- Check whether Glaucoma is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Apresoline:

Apresoline (2,475 reports)

Glaucoma treatments and more:

Glaucoma (61,928 reports)

Browse all side effects of Apresoline:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Glaucoma:

Glaucoma (1,233 drugs)

Browse all the conditions that are associated with Glaucoma:

Glaucoma (1,657 conditions)

Related publications that referenced our studies

Hu CY, Lee BJ, Cheng HF, Wang CY, "Acetazolamide-related life-threatening hypophosphatemia in a glaucoma patient", Journal of glaucoma, 2015 Apr .
Hu CY, Lee BJ, Cheng HF, Wang CY, "Acetazolamide-related life-threatening hypophosphatemia in a glaucoma patient", Journal of glaucoma, 2015 Apr .

How the study uses the data?

The study uses data from the FDA. It is based on hydralazine hydrochloride (the active ingredients of Apresoline) and Apresoline (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.