Trimethoprim and Avelox drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trimethoprim (trimethoprim) and Avelox (moxifloxacin hydrochloride). Common drug interactions include anhedonia among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Trimethoprim and Avelox. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Trimethoprim?

Trimethoprim has active ingredients of trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 8,213 Trimethoprim users. Check the latest studies of Trimethoprim.

What is Avelox?

Avelox has active ingredients of moxifloxacin hydrochloride. It is often used in sinusitis. eHealthMe is studying from 28,651 Avelox users. Check the latest studies of Avelox.

On Jul, 31, 2026

39 people who take Trimethoprim and Avelox together, and have interactions are studied.

Trimethoprim and Avelox drug interactions.

What are the common drug interactions of Trimethoprim and Avelox, by gender? *:

female:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Intervertebral disc protrusion (spinal disc protrusion)
Bone marrow failure
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Compression fracture (fracture due to pressure caused by injury)
Disability
Fracture
Hydrocephalus (water on the brain)
Injury
Ischaemia (insufficient supply of blood to an organ, usually due to a blocked artery)

male:

Chronic kidney disease
Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
Glomerulonephritis (a group of conditions that affect parts of the kidneys called glomeruli)
Hypokalaemia (low potassium)
Leukopenia (less number of white blood cells in blood)
Sepsis (a severe blood infection that can lead to organ failure and death)
Thrombocytopenia (decrease of platelets in blood)
Apraxia (disorder that affects a person's ability to organize the movements of the muscles used in speech)
Asthenia (weakness)
Dyspnoea (difficult or laboured respiration)

What are the common drug interactions of Trimethoprim and Avelox, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anxiety
Blood potassium decreased
Dyskinesia (abnormality or impairment of voluntary movement)
Emotional disorder
Excessive eye blinking (excessive blinking is dry eyes)
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Family stress
Gastritis (inflammation of stomach)
Impaired work ability
Pain

30-39:

Back pain
Cholecystitis chronic (long lasting infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Dyspepsia (indigestion)
Nausea (feeling of having an urge to vomit)

40-49:

Chronic kidney disease
Renal failure (kidney dysfunction)
Osteoporosis (bones weak and more likely to break)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal injury (kidney injury)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

50-59:

Bedridden
Bone marrow failure
Breast abscess
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Compression fracture (fracture due to pressure caused by injury)
Dehydration (dryness resulting from the removal of water)
Depression
Disability
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Facial pain

60+:

Chronic kidney disease
Anxiety
Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously)
Renal failure (kidney dysfunction)
Anaemia (lack of blood)
Asthenia (weakness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Bone marrow failure
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Compression fracture (fracture due to pressure caused by injury)

What are the existing conditions these people have? *

High Blood Pressure: 12 people, 30.77%
Neoplasm Malignant (cancer tumour): 10 people, 25.64%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 25.64%
Infection: 9 people, 23.08%
Pain: 6 people, 15.38%
Stress And Anxiety: 5 people, 12.82%
Panic Disorder: 5 people, 12.82%
High Blood Cholesterol: 5 people, 12.82%
Migraine (headache): 4 people, 10.26%
Depression: 4 people, 10.26%

* Approximation only. Some reports may have incomplete information.

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