Trimethoprim and Humalog drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trimethoprim (trimethoprim) and Humalog (insulin lispro recombinant). Common drug interactions include arteriosclerosis coronary artery among females and febrile neutropenia among males.

The phase IV clinical study analyzes what interactions people have when they take Trimethoprim and Humalog. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Trimethoprim?

Trimethoprim has active ingredients of trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 8,213 Trimethoprim users. Check the latest studies of Trimethoprim.

What is Humalog?

Humalog has active ingredients of insulin lispro recombinant. It is often used in diabetes. eHealthMe is studying from 137,127 Humalog users. Check the latest studies of Humalog.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 21, 2026

42 people who take Trimethoprim and Humalog together, and have interactions are studied.

Trimethoprim and Humalog drug interactions.

What are the common drug interactions of Trimethoprim and Humalog, by gender? *:

female:

Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Back pain
Blood glucose increased
Bone disorder
Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
Breath odour
Chest discomfort
Cholecystitis (infection of gallbladder)
Culture urine positive
Decreased appetite

male:

Febrile neutropenia (fever with reduced white blood cells)
Chronic kidney disease
Fall
Joint injury
Vision blurred
Abdominal distension
Arteriosclerosis (thickening and hardening of arteries)
Back pain
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Blepharospasm (any abnormal contraction or twitch of the eyelid)

What are the common drug interactions of Trimethoprim and Humalog, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Depression
Neutrophil count increased (excess than normal number of neutrophil a type of blood cell)
White blood cell count increased
Abdominal pain
Abdominal tenderness
Activities of daily living impaired
Aggression
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anaemia (lack of blood)
Anion gap increased

40-49:

Anal abscess
Genital abscess (build up of pus in genital)
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Abscess limb (limb infection)
Anxiety
Cellulitis (infection under the skin)
Groin abscess (pus in groin)
Nausea (feeling of having an urge to vomit)
Necrosis (the death of body tissue)
Pain

50-59:

White blood cell count increased
Abdominal pain
Actinomycosis (infection that causes sores, or abscesses)
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Back pain
Blindness unilateral
Blood glucose increased
Bone disorder
Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
Breath odour

60+:

Dizziness
Vision blurred
Abdominal pain
Anxiety
Asthenia (weakness)
Blindness unilateral
Blood glucose decreased
Cardiac failure congestive
Cough
Escherichia infection (bacterial infection by escherichia coli)

What are the existing conditions these people have? *

Type 2 Diabetes: 9 people, 21.43%
High Blood Pressure: 9 people, 21.43%
High Blood Cholesterol: 7 people, 16.67%
Anaemia (lack of blood): 7 people, 16.67%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 5 people, 11.90%
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 5 people, 11.90%
Hypokalemia (low potassium): 5 people, 11.90%
Hypocalcaemia (levels of calcium in blood serum are abnormally low): 5 people, 11.90%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 5 people, 11.90%
Pain: 4 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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