Trimethoprim and Imdur drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trimethoprim (trimethoprim) and Imdur (isosorbide mononitrate). Common drug interactions include bone pain among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Trimethoprim and Imdur. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Trimethoprim?

Trimethoprim has active ingredients of trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 8,213 Trimethoprim users. Check the latest studies of Trimethoprim.

What is Imdur?

Imdur has active ingredients of isosorbide mononitrate. It is often used in angina. eHealthMe is studying from 17,367 Imdur users. Check the latest studies of Imdur.

On Jul, 10, 2026

23 people who take Trimethoprim and Imdur together, and have interactions are studied.

Trimethoprim and Imdur drug interactions.

What are the common drug interactions of Trimethoprim and Imdur, by gender? *:

female:

Bone pain
Constipation
Diarrhoea
Hypokalaemia (low potassium)
Nausea (feeling of having an urge to vomit)
Palpitations (feelings or sensations that your heart is pounding or racing)
Acute respiratory distress syndrome
Acute respiratory failure
Age-related macular degeneration
Cardiac failure

male:

Diarrhoea
Chest pain
Asthenia (weakness)
Back pain
Balance disorder
Blood pressure decreased
Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
Conjunctivitis (pink eye)
Decreased appetite
Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)

What are the common drug interactions of Trimethoprim and Imdur, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

50-59:

n/a

60+:

Diarrhoea
Hypokalaemia (low potassium)
Cardiac failure
Confusional state
Depression
Hallucination, auditory (perceiving sounds without auditory stimulus)
Hyperkalaemia (damage to or disease of the kidney)
Maculopathy (a condition or disease of the macula, the small spot in the retina where vision is keenest)
Retinal tear
Abdominal hernia

What are the existing conditions these people have? *

Diffuse Large B-Cell Lymphoma Stage Iii (cancer of b cells, a type of white blood cell-stage iii): 6 people, 26.09%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 5 people, 21.74%
Hypokalemia (low potassium): 4 people, 17.39%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 13.04%
High Blood Cholesterol: 3 people, 13.04%
High Blood Pressure: 3 people, 13.04%
Hyperglycemia (high blood sugar): 2 people, 8.70%
Back Pain: 2 people, 8.70%
Bladder Disorder: 2 people, 8.70%
Constipation: 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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