Trimox and Metformin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trimox (amoxicillin) and Metformin (metformin hydrochloride). Common drug interactions include dysuria among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Trimox and Metformin. It is created by eHealthMe based on reports of 62 people who take the same drugs from the FDA, and is updated regularly.

What is Trimox?

Trimox has active ingredients of amoxicillin. eHealthMe is studying from 932 Trimox users. Check the latest studies of Trimox.

What is Metformin?

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 465,355 Metformin users. Check the latest studies of Metformin.

On Aug, 07, 2026

62 people who take Trimox and Metformin together, and have interactions are studied.

What are the common drug interactions of Trimox and Metformin, by gender? *:

female:

Dysuria (painful or difficult urination)
Fatigue (feeling of tiredness)
Hyperlipidaemia (presence of excess lipids in the blood)
Hypertension (high blood pressure)
International normalised ratio decreased
Multiple injuries
Sneezing
Surgery
Tremor (trembling or shaking movements in one or more parts of your body)
Dyspnoea (difficult or laboured respiration)

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Hyperhidrosis (abnormally increased sweating)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Palpitations (feelings or sensations that your heart is pounding or racing)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Chest pain
Dyspnoea (difficult or laboured respiration)
Exposure to toxic agent
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)

What are the common drug interactions of Trimox and Metformin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Chronic kidney disease

30-39:

Anxiety
Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode)
Fibromyalgia (a long-term condition which causes pain all over the body)
Mania (a state of abnormally elevated or irritable mood)
Neuropathy peripheral (surface nerve damage)
Renal failure (kidney dysfunction)
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
Acanthosis (thickening of the skin)
Arthralgia (joint pain)
Blood cholesterol increased

40-49:

Chronic kidney disease
Renal failure (kidney dysfunction)
Anger
Angina pectoris (chest pain due to ischemia of the heart muscle)
Asthma
Attention deficit/hyperactivity disorder
Back disorder
Chest pain
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Disturbance in attention

50-59:

Hypertension (high blood pressure)
International normalised ratio decreased
Multiple injuries
Sneezing
Surgery
Tremor (trembling or shaking movements in one or more parts of your body)
Dyspepsia (indigestion)
Fall
Renal injury (kidney injury)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Hyperhidrosis (abnormally increased sweating)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Palpitations (feelings or sensations that your heart is pounding or racing)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Exposure to toxic agent
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cardiac murmur (an heart sound in valve abnormality)
Cardiomegaly (increased size of heart than normal)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 34 people, 54.84%
Pain: 24 people, 38.71%
Depression: 17 people, 27.42%
Cardiac Disorder: 16 people, 25.81%
High Blood Cholesterol: 12 people, 19.35%
Stress And Anxiety: 11 people, 17.74%
High Blood Pressure: 11 people, 17.74%
Infection: 9 people, 14.52%
Fluid Retention (an abnormal accumulation of fluid in the blood): 7 people, 11.29%
Nausea (feeling of having an urge to vomit): 6 people, 9.68%

* Approximation only. Some reports may have incomplete information.

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