Trinalin and Synthroid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trinalin (azatadine maleate; pseudoephedrine sulfate) and Synthroid (levothyroxine sodium). Common drug interactions include atrial fibrillation among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Trinalin and Synthroid. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Trinalin?

Trinalin has active ingredients of azatadine maleate; pseudoephedrine sulfate. eHealthMe is studying from 108 Trinalin users. Check the latest studies of Trinalin.

What is Synthroid?

Synthroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 249,202 Synthroid users. Check the latest studies of Synthroid.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 15, 2026

13 people who take Trinalin and Synthroid together, and have interactions are studied.

Trinalin and Synthroid drug interactions.

What are the common drug interactions of Trinalin and Synthroid, by gender? *:

female:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blood cholesterol increased
Blood disorder
Bradycardia (abnormally slow heart action)
Carotid artery stenosis (narrowing of carotid artery)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Confusional state
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Cough
Depression

male:

Drug ineffective
Impotence (powerlessness)
Anorgasmia (type of sexual dysfunction in which a person cannot achieve orgasm, even with adequate stimulation)
Libido decreased (loss of interest in sex)
Oesophageal haemorrhage (bleeding from oesophagus)

What are the common drug interactions of Trinalin and Synthroid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Dry mouth
Headache (pain in head)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Insomnia (sleeplessness)
Oedema (fluid collection in tissue)
Palpitations (feelings or sensations that your heart is pounding or racing)
Sweating increased (excess sweating)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Tooth disorder (tooth disease)
Tremor (trembling or shaking movements in one or more parts of your body)

50-59:

n/a

60+:

Acute myocardial infarction (acute heart attack)
Alopecia (absence of hair from areas of the body)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Confusional state
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Cough
Depression
Drug ineffective
Dyspnoea (difficult or laboured respiration)
Embolic stroke (stroke due to obstruction due to an embolus)

What are the existing conditions these people have? *

Pain In Extremity: 2 people, 15.38%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 2 people, 15.38%

* Approximation only. Some reports may have incomplete information.

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