Trintellix and Glipizide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trintellix (vortioxetine hydrobromide) and Glipizide (glipizide). Common drug interactions include rash erythematous among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Trintellix and Glipizide. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Trintellix?

Trintellix has active ingredients of vortioxetine hydrobromide. It is often used in depression. eHealthMe is studying from 13,067 Trintellix users. Check the latest studies of Trintellix.

What is Glipizide?

Glipizide has active ingredients of glipizide. It is often used in diabetes. eHealthMe is studying from 64,852 Glipizide users. Check the latest studies of Glipizide.

On Jul, 14, 2026

29 people who take Trintellix and Glipizide together, and have interactions are studied.

Trintellix and Glipizide drug interactions.

What are the common drug interactions of Trintellix and Glipizide, by gender? *:

female:

Rash erythematous (redness of the skin)
Chronic kidney disease
Drug ineffective
Fatigue (feeling of tiredness)
Headache (pain in head)
Insomnia (sleeplessness)
Nausea (feeling of having an urge to vomit)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Pruritus (severe itching of the skin)
Rash

male:

Fatigue (feeling of tiredness)
Memory impairment
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Tinnitus (a ringing in the ears)
Gastrointestinal motility disorder (abnormal intestinal contractions)
Heart rate increased
Impulsive behaviour
Laziness
Restlessness (not able to rest)
Abdominal discomfort

What are the common drug interactions of Trintellix and Glipizide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)

40-49:

Chronic kidney disease
Abdominal pain
Alopecia (absence of hair from areas of the body)
Back pain
Chest discomfort
Drug ineffective
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Fibromyalgia (a long-term condition which causes pain all over the body)
Headache (pain in head)

50-59:

Rash erythematous (redness of the skin)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Heart rate increased
Impulsive behaviour
Memory impairment
Pruritus (severe itching of the skin)
Rash
Suicidal ideation
Weight decreased
Anhedonia (inability to experience pleasure from activities usually found enjoyable)

60+:

Headache (pain in head)
Neuropathy peripheral (surface nerve damage)
Increased tendency to bruise (increased tendency to injure the underlying soft tissue or bone)
Insomnia (sleeplessness)
Malaise (a feeling of general discomfort or uneasiness)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Nausea (feeling of having an urge to vomit)
Obstruction
Pneumonia
Pruritus (severe itching of the skin)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 27.59%
Stress And Anxiety: 7 people, 24.14%
Type 2 Diabetes: 6 people, 20.69%
High Blood Pressure: 6 people, 20.69%
Pain: 6 people, 20.69%
Neuropathy Peripheral (surface nerve damage): 5 people, 17.24%
Migraine (headache): 5 people, 17.24%
Neuralgia (pain in one or more nerves): 4 people, 13.79%
Thrombosis (formation of a blood clot inside a blood vessel): 3 people, 10.34%
Blood Pressure Abnormal: 3 people, 10.34%

* Approximation only. Some reports may have incomplete information.

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