Trintellix and Kesimpta drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trintellix (vortioxetine hydrobromide) and Kesimpta (ofatumumab). Common drug interactions include headache among females and dizziness among males.

The phase IV clinical study analyzes what interactions people have when they take Trintellix and Kesimpta. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Trintellix?

Trintellix has active ingredients of vortioxetine hydrobromide. It is often used in depression. eHealthMe is studying from 13,067 Trintellix users. Check the latest studies of Trintellix.

What is Kesimpta?

Kesimpta has active ingredients of ofatumumab. eHealthMe is studying from 36,592 Kesimpta users. Check the latest studies of Kesimpta.

On Jul, 18, 2026

25 people who take Trintellix and Kesimpta together, and have interactions are studied.

Trintellix and Kesimpta drug interactions.

What are the common drug interactions of Trintellix and Kesimpta, by gender? *:

female:

Headache (pain in head)
Hyperhidrosis (abnormally increased sweating)
Feeling hot
Pruritus (severe itching of the skin)
Nausea (feeling of having an urge to vomit)
Chills (felling of cold)
Cellulitis (infection under the skin)
Pain
Rash
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

male:

Dizziness
Abdominal pain
Constipation
Diarrhoea
Dysuria (painful or difficult urination)
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Fatigue (feeling of tiredness)
Feeling cold
Gout (uric acid crystals building up in the body)
Headache (pain in head)

What are the common drug interactions of Trintellix and Kesimpta, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Dizziness
Abdominal pain
Abdominal pain lower
Abdominal pain upper
Anxiety
Arthralgia (joint pain)
Asthenia (weakness)
Back pain
Blood alkaline phosphatase increased
Central nervous system lesion (an abnormality in tissue of brain or spinal cord)

40-49:

Chills (felling of cold)
Pyrexia (fever)
Swelling face
Vomiting
Cellulitis (infection under the skin)
Feeling hot
Hyperhidrosis (abnormally increased sweating)
Pruritus (severe itching of the skin)
Depressed mood
Infection

50-59:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Clumsiness (a lack of coordination or elegance)
Headache (pain in head)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)

60+:

n/a

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 13 people, 52.00%

* Approximation only. Some reports may have incomplete information.

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