Trintellix and Valium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trintellix (vortioxetine hydrobromide) and Valium (diazepam). Common drug interactions include seizure like phenomena among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Trintellix and Valium. It is created by eHealthMe based on reports of 95 people who take the same drugs from the FDA, and is updated regularly.

What is Trintellix?

Trintellix has active ingredients of vortioxetine hydrobromide. It is often used in depression. eHealthMe is studying from 13,067 Trintellix users. Check the latest studies of Trintellix.

What is Valium?

Valium has active ingredients of diazepam. It is often used in stress and anxiety. eHealthMe is studying from 48,647 Valium users. Check the latest studies of Valium.

On Jul, 15, 2026

95 people who take Trintellix and Valium together, and have interactions are studied.

Trintellix and Valium drug interactions.

What are the common drug interactions of Trintellix and Valium, by gender? *:

female:

Seizure like phenomena (a variety of medical conditions may produce sudden episodes which have some similarities to epileptic seizures)
Weight decreased
Abdominal discomfort
Dizziness
Weight increased
Anger
Cellulitis (infection under the skin)
Balance disorder
Blood pressure increased
Hypoacusis (loss of hearing)

male:

Diarrhoea
Fall
Suicidal ideation
Anger
Appetite disorder (abnormal eating habits)
Brain injury
Concussion (short loss of normal brain function in response to a head injury)
Dizziness
Drug ineffective
Dry mouth

What are the common drug interactions of Trintellix and Valium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Affective disorder (mental disorder)
Asthenia (weakness)
Confusional state
Emotional distress
Fatigue (feeling of tiredness)
Head injury
Pain
Seizure like phenomena (a variety of medical conditions may produce sudden episodes which have some similarities to epileptic seizures)
Tremor (trembling or shaking movements in one or more parts of your body)
Cataplexy (loss of muscle tone accompanied by full conscious awareness)

30-39:

Balance disorder
Dizziness
Drug ineffective
Heart rate increased
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
Weight decreased
Kidney infection
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Tooth extraction
Blood creatinine increased

40-49:

Suicidal ideation
Abdominal discomfort
Adverse reaction
Agitation (state of anxiety or nervous excitement)
Anger
Blood pressure increased
Mydriasis (a dilation of the pupil)
Ocular discomfort (a generic expression when there is lack of ease in/about the eyes)
Pyrexia (fever)
Rash

50-59:

Drug ineffective
Flushing (the warm, red condition of human skin)
Hypertension (high blood pressure)
Insomnia (sleeplessness)
Loss of consciousness
Pharyngeal hypoaesthesia (pharyngeal -abnormally decreased sensitivity)
Pruritus (severe itching of the skin)
Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

60+:

Diarrhoea
Fall
Appetite disorder (abnormal eating habits)
Dizziness
Intervertebral disc injury (spinal disc injury)
Nausea (feeling of having an urge to vomit)
Gait disturbance
Vision blurred
Vomiting
Balance disorder

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 16 people, 16.84%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 13 people, 13.68%
Pain: 9 people, 9.47%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 7.37%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 6.32%
Migraine (headache): 6 people, 6.32%
Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 5 people, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Trintellix and Valium?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously