Trulance and Lasix drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Trulance (plecanatide) and Lasix (furosemide). Common drug interactions include constipation among females and aphonia among males.
The phase IV clinical study analyzes what interactions people have when they take Trulance and Lasix. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.
What is Trulance?
Trulance has active ingredients of plecanatide. eHealthMe is studying from 1,746 Trulance users. Check the latest studies of Trulance.
What is Lasix?
Lasix has active ingredients of furosemide. It is often used in swelling. eHealthMe is studying from 210,439 Lasix users. Check the latest studies of Lasix.
22 people who take Trulance and Lasix together, and have interactions are studied.

What are the common drug interactions of Trulance and Lasix, by gender? *:
female:
- Constipation
- Dizziness
- Fall
- Abdominal pain upper
- Cystitis (inflammation of the wall of the bladder)
- Dyspnoea (difficult or laboured respiration)
- Dysuria (painful or difficult urination)
- Fatigue (feeling of tiredness)
- Feeling hot
- Foot deformity (functional disability of foot)
male:
- Aphonia (inability to produce voice)
- Dehydration (dryness resulting from the removal of water)
- Diarrhoea
- Fatigue (feeling of tiredness)
- Malaise (a feeling of general discomfort or uneasiness)
- Oropharyngeal pain
- Overdose
- Stomatitis (inflammation of mucous membrane of mouth)
- Surgery
What are the common drug interactions of Trulance and Lasix, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Bowel movement irregularity
- Dehydration (dryness resulting from the removal of water)
- Diarrhoea
- Erythema of eyelid (redness of the eyelid)
- Eye discharge
- Ocular hyperaemia (an abnormally large amount of blood in eye)
50-59:
- Chest pain
- Diarrhoea
- Pain in jaw
- Antinuclear antibody positive
- Anxiety
- Back pain
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
- Body temperature increased
- Bowen's disease (early stage of skin cancer)
- Carbon dioxide increased
60+:
- Constipation
- Diarrhoea
- Foot deformity (functional disability of foot)
- Headache (pain in head)
- Infusion site pain
- Malaise (a feeling of general discomfort or uneasiness)
- Pain
- Procedural pain
- Renal impairment (severely reduced kidney function)
- Rib fracture
What are the existing conditions these people have? *
- Constipation: 6 people, 27.27%
- Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously): 4 people, 18.18%
- Stress And Anxiety: 2 people, 9.09%
- Pain: 2 people, 9.09%
- Nerve Injury: 2 people, 9.09%
- Irritable Bowel Syndrome: 2 people, 9.09%
- High Blood Pressure: 2 people, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Trulance and Lasix?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Trulance and Lasix:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Trulance:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Lasix:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Trulance and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lasix and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Ochoa PS, Fisher T, "A 7‐Year Case of Furosemide‐Induced Immune Thrombocytopenia", Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 2013 Jul .
- Ochoa PS, Fisher T, "A 7‐Year Case of Furosemide‐Induced Immune Thrombocytopenia", Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 2013 Jul .
How the study uses the data?
The study uses data from the FDA. It is based on plecanatide and furosemide (the active ingredients of Trulance and Lasix, respectively), and Trulance and Lasix (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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