Trulicity and Aubagio drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Trulicity (dulaglutide) and Aubagio (teriflunomide). Common drug interactions include depression among females and fatigue among males.
The phase IV clinical study analyzes what interactions people have when they take Trulicity and Aubagio. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.
What is Trulicity?
Trulicity has active ingredients of dulaglutide. It is often used in weight loss. eHealthMe is studying from 77,529 Trulicity users. Check the latest studies of Trulicity.
What is Aubagio?
Aubagio has active ingredients of teriflunomide. It is often used in multiple sclerosis. eHealthMe is studying from 50,041 Aubagio users. Check the latest studies of Aubagio.
36 people who take Trulicity and Aubagio together, and have interactions are studied.

What are the common drug interactions of Trulicity and Aubagio, by gender? *:
female:
- Depression
- Diarrhoea
- Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
- Alopecia (absence of hair from areas of the body)
- Fall
- Asthenia (weakness)
- Pain in extremity
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Gait disturbance
- Gastritis (inflammation of stomach)
male:
- Fatigue (feeling of tiredness)
- Hypertension (high blood pressure)
- Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
- Anxiety
- Asthenia (weakness)
- Balance disorder
- Chest injury
- Constipation
- Decreased appetite
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
What are the common drug interactions of Trulicity and Aubagio, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Diarrhoea
- Muscular weakness (muscle weakness)
- Alopecia (absence of hair from areas of the body)
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Ataxia (loss of full control of bodily movements)
- Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
- Fall
- Gait disturbance
- Gastritis (inflammation of stomach)
- Intervertebral disc degeneration (spinal disc degeneration)
50-59:
- Fall
- Fatigue (feeling of tiredness)
- Diarrhoea
- Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
- Alopecia (absence of hair from areas of the body)
- Anxiety
- Asthenia (weakness)
- Balance disorder
- Blood glucose increased
- Chest injury
60+:
- Hypertension (high blood pressure)
- Hypoaesthesia (reduced sense of touch or sensation)
- Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
- Abdominal discomfort
- Dysgeusia (disorder of the sense of taste)
- Eructation (release of gas from the digestive tract)
- Alopecia (absence of hair from areas of the body)
- Asthenia (weakness)
- Chronic kidney disease
- Depression
What are the existing conditions these people have? *
- Nausea (feeling of having an urge to vomit): 2 people, 5.56%
- High Blood Pressure: 2 people, 5.56%
- High Blood Cholesterol: 2 people, 5.56%
- Headache (pain in head): 2 people, 5.56%
- Gait Disturbance: 2 people, 5.56%
* Approximation only. Some reports may have incomplete information.
Do you take Trulicity and Aubagio?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Trulicity and Aubagio:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Trulicity:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Aubagio:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Trulicity and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Aubagio and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on dulaglutide and teriflunomide (the active ingredients of Trulicity and Aubagio, respectively), and Trulicity and Aubagio (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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