Trulicity and Calcitriol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trulicity (dulaglutide) and Calcitriol (calcitriol). Common drug interactions include oedema peripheral among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Trulicity and Calcitriol. It is created by eHealthMe based on reports of 60 people who take the same drugs from the FDA, and is updated regularly.

What is Trulicity?

Trulicity has active ingredients of dulaglutide. It is often used in weight loss. eHealthMe is studying from 77,529 Trulicity users. Check the latest studies of Trulicity.

What is Calcitriol?

Calcitriol has active ingredients of calcitriol. It is often used in hypoparathyroidism. eHealthMe is studying from 24,162 Calcitriol users. Check the latest studies of Calcitriol.



On Jul, 15, 2026

60 people who take Trulicity and Calcitriol together, and have interactions are studied.

Trulicity and Calcitriol drug interactions.

What are the common drug interactions of Trulicity and Calcitriol, by gender? *:

female:

  1. Oedema peripheral (superficial swelling)
  2. Oropharyngeal pain
  3. Pain
  4. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  5. Photophobia (extreme sensitivity to light)
  6. Rash
  7. Rash erythematous (redness of the skin)
  8. Rash generalised (rash on most of body parts)
  9. Rash pruritic (redness with itching)
  10. Renal necrosis (kidney damaged)

male:

  1. Chronic kidney disease
  2. Death
  3. Blood magnesium decreased
  4. Decreased appetite
  5. Dysgeusia (disorder of the sense of taste)
  6. Dyspnoea (difficult or laboured respiration)
  7. Fatigue (feeling of tiredness)
  8. Glycosylated haemoglobin increased
  9. Insomnia (sleeplessness)
  10. Productive cough

What are the common drug interactions of Trulicity and Calcitriol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Hyperkalaemia (damage to or disease of the kidney)
  2. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  3. Nephrogenic anaemia (anaemia due to kidney disease)
  4. Orchitis (inflammation of the testes)
  5. Scrotal abscess (pus in scrotum)
  6. Sepsis (a severe blood infection that can lead to organ failure and death)
  7. Urinary tract infection
  8. Abscess limb (limb infection)
  9. Cellulitis of male external genital organ (infection of male genitals soft tissue)
  10. Chronic kidney disease

30-39:

n/a

40-49:

  1. Fatigue (feeling of tiredness)
  2. Malaise (a feeling of general discomfort or uneasiness)
  3. Back pain
  4. Cutaneous lupus erythematosus (own immune system attacks various cells causing a wide variety of signs and symptoms)
  5. Drug hypersensitivity
  6. Dyspnoea (difficult or laboured respiration)
  7. Headache (pain in head)
  8. Blood glucose fluctuation
  9. Blood magnesium decreased
  10. Blood thyroid stimulating hormone increased

50-59:

  1. Chronic kidney disease
  2. Nephrogenic anaemia (anaemia due to kidney disease)
  3. Renal failure (kidney dysfunction)
  4. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  5. Blood creatinine increased
  6. Dizziness
  7. Drug ineffective
  8. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  9. Glomerular filtration rate decreased
  10. Hyperkalaemia (damage to or disease of the kidney)

60+:

  1. Decreased appetite
  2. Chronic kidney disease
  3. Blood magnesium decreased
  4. Dysgeusia (disorder of the sense of taste)
  5. Dyspnoea (difficult or laboured respiration)
  6. Fatigue (feeling of tiredness)
  7. Glycosylated haemoglobin increased
  8. Insomnia (sleeplessness)
  9. Productive cough
  10. Ageusia (loss of taste functions of the tongue)

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 12 people, 20.00%
  2. High Blood Cholesterol: 10 people, 16.67%
  3. Pain: 9 people, 15.00%
  4. Type 2 Diabetes: 8 people, 13.33%
  5. Diabetes: 8 people, 13.33%
  6. High Blood Pressure: 8 people, 13.33%
  7. Hereditary Angioedema (recurrent episodes of severe swelling): 7 people, 11.67%
  8. Multiple Myeloma (cancer of the plasma cells): 6 people, 10.00%
  9. Myasthenia Gravis (a chronic condition that causes muscles to tire and weaken easily): 5 people, 8.33%
  10. Cardiac Disorder: 4 people, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Trulicity and Calcitriol?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Trulicity and Calcitriol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Trulicity:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Calcitriol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Trulicity and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Calcitriol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on dulaglutide and calcitriol (the active ingredients of Trulicity and Calcitriol, respectively), and Trulicity and Calcitriol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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