Trulicity and Euthyrox drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Trulicity (dulaglutide) and Euthyrox (levothyroxine sodium). Common drug interactions include blood pressure increased among females and blood creatine phosphokinase increased among males.
The phase IV clinical study analyzes what interactions people have when they take Trulicity and Euthyrox. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.
What is Trulicity?
Trulicity has active ingredients of dulaglutide. It is often used in weight loss. eHealthMe is studying from 77,529 Trulicity users. Check the latest studies of Trulicity.
What is Euthyrox?
Euthyrox has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 8,740 Euthyrox users. Check the latest studies of Euthyrox.
25 people who take Trulicity and Euthyrox together, and have interactions are studied.

What are the common drug interactions of Trulicity and Euthyrox, by gender? *:
female:
- Blood pressure increased
- Diarrhoea
- Drug ineffective
- Bacterial infection
- Decreased appetite
- Dysgeusia (disorder of the sense of taste)
- Dyspepsia (indigestion)
- Influenza
- Limb malformation (abnormal birth defect of leg)
- Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
male:
- Blood creatine phosphokinase increased
- Blood creatine phosphokinase mb increased
- Skin exfoliation (removal of the oldest dead skin cells)
- Skin fissures (a crack in the skin)
- Therapeutic response decreased (less preventive response)
- Transaminases increased
- Blood glucose increased
- Drug ineffective
- Cardiac failure congestive
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
What are the common drug interactions of Trulicity and Euthyrox, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Limb malformation (abnormal birth defect of leg)
- Osteomyelitis (infection of bone)
- Body mass index increased
- Pruritus (severe itching of the skin)
- Thyroid cancer
50-59:
- Bacterial infection
- Blood creatine phosphokinase increased
- Blood creatine phosphokinase mb increased
- Blood creatinine increased
- Blood urea increased
- Decreased appetite
- Diarrhoea
- Dry skin
- Dysgeusia (disorder of the sense of taste)
- Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
60+:
- Blood pressure increased
- Drug ineffective
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
- Diarrhoea
- Disease recurrence
- Disorientation (disability in which the senses of time, direction, and recognition of people and places)
- Disturbance in attention
- Eye pain
- Eyelid pain
What are the existing conditions these people have? *
- Type 2 Diabetes: 6 people, 24.00%
- Diabetes: 6 people, 24.00%
- High Blood Pressure: 5 people, 20.00%
- Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 3 people, 12.00%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 8.00%
* Approximation only. Some reports may have incomplete information.
Do you take Trulicity and Euthyrox?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Trulicity and Euthyrox:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Trulicity:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Euthyrox:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Trulicity and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Euthyrox and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on dulaglutide and levothyroxine sodium (the active ingredients of Trulicity and Euthyrox, respectively), and Trulicity and Euthyrox (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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