Trulicity and Hizentra drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Trulicity (dulaglutide) and Hizentra (human immunoglobulin g). Common drug interactions include sinusitis among females and fatigue among males.
The phase IV clinical study analyzes what interactions people have when they take Trulicity and Hizentra. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.
What is Trulicity?
Trulicity has active ingredients of dulaglutide. It is often used in weight loss. eHealthMe is studying from 77,529 Trulicity users. Check the latest studies of Trulicity.
What is Hizentra?
Hizentra has active ingredients of human immunoglobulin g. eHealthMe is studying from 23,666 Hizentra users. Check the latest studies of Hizentra.
42 people who take Trulicity and Hizentra together, and have interactions are studied.

What are the common drug interactions of Trulicity and Hizentra, by gender? *:
female:
- Sinusitis (inflammation of sinus)
- Escherichia urinary tract infection (urinary tract infection by escherichia coli)
- Asthenia (weakness)
- Pyrexia (fever)
- Arthralgia (joint pain)
- Headache (pain in head)
- Mobility decreased (ability to move is reduced)
- Oral candidiasis (fungal infection of mouth)
- Rash
- Blindness unilateral
male:
- Fatigue (feeling of tiredness)
- Balance disorder
- Death
- Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
- Drug ineffective
- Gallbladder disorder
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Sinusitis (inflammation of sinus)
What are the common drug interactions of Trulicity and Hizentra, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Platelet count decreased
40-49:
- Blood glucose increased
- Injection site erythema (redness at injection site)
50-59:
- Rash
- Arthralgia (joint pain)
- Oral candidiasis (fungal infection of mouth)
- Malaise (a feeling of general discomfort or uneasiness)
- Ulcer
- Fatigue (feeling of tiredness)
- Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
- Headache (pain in head)
- Depression
- Drug ineffective
60+:
- Escherichia urinary tract infection (urinary tract infection by escherichia coli)
- Mobility decreased (ability to move is reduced)
- Brain neoplasm (tumour of brain)
- Post procedural complication
- Sinusitis (inflammation of sinus)
- Dehydration (dryness resulting from the removal of water)
- Hypotension (abnormally low blood pressure)
- Influenza
- Loss of consciousness
- Pain
What are the existing conditions these people have? *
- Immunodeficiency Common Variable: 20 people, 47.62%
- High Blood Pressure: 9 people, 21.43%
- High Blood Cholesterol: 9 people, 21.43%
- Diabetes: 9 people, 21.43%
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 9 people, 21.43%
- Migraine (headache): 9 people, 21.43%
- Insomnia (sleeplessness): 9 people, 21.43%
- Immunodeficiency: 9 people, 21.43%
- Atrophic Vulvovaginitis (inflammation of the vulva): 8 people, 19.05%
- Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 8 people, 19.05%
* Approximation only. Some reports may have incomplete information.
Do you take Trulicity and Hizentra?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Trulicity and Hizentra:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Trulicity:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Hizentra:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Trulicity and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Hizentra and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on dulaglutide and human immunoglobulin g (the active ingredients of Trulicity and Hizentra, respectively), and Trulicity and Hizentra (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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