Trulicity and Hydroxyurea drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trulicity (dulaglutide) and Hydroxyurea (hydroxyurea). Common drug interactions include alopecia among females and decreased appetite among males.

The phase IV clinical study analyzes what interactions people have when they take Trulicity and Hydroxyurea. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Trulicity?

Trulicity has active ingredients of dulaglutide. It is often used in weight loss. eHealthMe is studying from 77,529 Trulicity users. Check the latest studies of Trulicity.

What is Hydroxyurea?

Hydroxyurea has active ingredients of hydroxyurea. It is often used in polycythemia vera. eHealthMe is studying from 17,240 Hydroxyurea users. Check the latest studies of Hydroxyurea.

On Jul, 12, 2026

23 people who take Trulicity and Hydroxyurea together, and have interactions are studied.

Trulicity and Hydroxyurea drug interactions.

What are the common drug interactions of Trulicity and Hydroxyurea, by gender? *:

female:

Alopecia (absence of hair from areas of the body)
Pancreatitis (inflammation of pancreas)
Injection site pruritus (severe itching at injection site)
Nausea (feeling of having an urge to vomit)
Urinary tract infection
Weight decreased
Nephrolithiasis (calculi in the kidneys)
Night sweats (sweating in night)
Abdominal discomfort
Administration site pain

male:

Decreased appetite
Diarrhoea
Dry skin
Platelet count decreased
Pruritus (severe itching of the skin)
Sepsis (a severe blood infection that can lead to organ failure and death)
Skin fissures (a crack in the skin)
Skin haemorrhage (bleeding into skin)
White blood cell count decreased
Flatulence (flatus expelled through the anus)

What are the common drug interactions of Trulicity and Hydroxyurea, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Alopecia (absence of hair from areas of the body)
Back pain
Chills (felling of cold)
Death
Eyelid ptosis (falling of the upper or lower eyelid)
Haemoglobin decreased
Platelet count decreased
Sepsis (a severe blood infection that can lead to organ failure and death)
White blood cell count decreased

What are the existing conditions these people have? *

Essential Thrombocythaemia (chronic blood cancer): 5 people, 21.74%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 4 people, 17.39%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 3 people, 13.04%
Hidradenitis (chronic disease of a type of sweat gland): 3 people, 13.04%
Type 2 Diabetes: 2 people, 8.70%
Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 2 people, 8.70%
High Blood Pressure: 2 people, 8.70%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 8.70%
Chronic Left Ventricular Failure (long lasting functional impairment of left ventricle of heart): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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