Trulicity and Hydroxyzine pamoate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trulicity (dulaglutide) and Hydroxyzine pamoate (hydroxyzine pamoate). Common drug interactions include diarrhoea among females and gastrooesophageal reflux disease among males.

The phase IV clinical study analyzes what interactions people have when they take Trulicity and Hydroxyzine pamoate. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Trulicity?

Trulicity has active ingredients of dulaglutide. It is often used in weight loss. eHealthMe is studying from 77,529 Trulicity users. Check the latest studies of Trulicity.

What is Hydroxyzine pamoate?

Hydroxyzine pamoate has active ingredients of hydroxyzine pamoate. It is often used in stress and anxiety. eHealthMe is studying from 4,252 Hydroxyzine pamoate users. Check the latest studies of Hydroxyzine pamoate.

On Jul, 24, 2026

20 people who take Trulicity and Hydroxyzine pamoate together, and have interactions are studied.

Trulicity and Hydroxyzine pamoate drug interactions.

What are the common drug interactions of Trulicity and Hydroxyzine Pamoate, by gender? *:

female:

Diarrhoea
Hypertension (high blood pressure)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Drug hypersensitivity
Nausea (feeling of having an urge to vomit)
Abdominal discomfort
Abnormal behaviour
Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
Discomfort
Drug ineffective

male:

Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Abdominal distension
Back pain
Diarrhoea
Eructation (release of gas from the digestive tract)
Gingival pain (gum pain)
Rash
Weight decreased
Chronic kidney disease
Renal failure (kidney dysfunction)

What are the common drug interactions of Trulicity and Hydroxyzine Pamoate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Balance disorder
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diarrhoea
Drug hypersensitivity
Herpes zoster
Nausea (feeling of having an urge to vomit)
Neuropathy peripheral (surface nerve damage)

40-49:

Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
Discomfort
Rash
Sleep disorder
Ulcer
Chronic kidney disease
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Renal failure (kidney dysfunction)

50-59:

Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
Cardiac murmur (an heart sound in valve abnormality)
Cataract (clouding of the lens inside the eye)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Fatigue (feeling of tiredness)
Hyperhidrosis (abnormally increased sweating)
Hypertension (high blood pressure)
Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)

60+:

Adverse drug reaction
Chronic kidney disease
Confusional state
Drug hypersensitivity
Facial paralysis (loss of function of face muscle)
Hypoaesthesia (reduced sense of touch or sensation)
Somnolence (a state of near-sleep, a strong desire for sleep)
Unresponsive to stimuli

What are the existing conditions these people have? *

Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 25.00%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 25.00%
Pain: 3 people, 15.00%
Type 2 Diabetes: 2 people, 10.00%
Immunodeficiency Common Variable: 2 people, 10.00%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 2 people, 10.00%
Diabetes: 2 people, 10.00%
Drowsiness: 2 people, 10.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 10.00%
Immunodeficiency: 2 people, 10.00%

* Approximation only. Some reports may have incomplete information.

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