Trulicity and Loperamide hydrochloride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trulicity (dulaglutide) and Loperamide hydrochloride (loperamide hydrochloride). Common drug interactions include bronchitis among females and body mass index increased among males.

The phase IV clinical study analyzes what interactions people have when they take Trulicity and Loperamide hydrochloride. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Trulicity?

Trulicity has active ingredients of dulaglutide. It is often used in weight loss. eHealthMe is studying from 77,529 Trulicity users. Check the latest studies of Trulicity.

What is Loperamide hydrochloride?

Loperamide hydrochloride has active ingredients of loperamide hydrochloride. It is often used in diarrhea. eHealthMe is studying from 10,814 Loperamide hydrochloride users. Check the latest studies of Loperamide hydrochloride.



On Jul, 04, 2026

25 people who take Trulicity and Loperamide hydrochloride together, and have interactions are studied.

Trulicity and Loperamide hydrochloride drug interactions.

What are the common drug interactions of Trulicity and Loperamide Hydrochloride, by gender? *:

female:

  1. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  2. Pneumonia
  3. Chronic left ventricular failure (long lasting functional impairment of left ventricle of heart)
  4. Dry eye (lack of adequate tears)
  5. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  6. Renal disorder (kidney disease)
  7. Blood glucose decreased
  8. Crying
  9. Decreased appetite
  10. Dehydration (dryness resulting from the removal of water)

male:

  1. Body mass index increased
  2. Dyslipidaemia (abnormal amount of lipids)
  3. Blood glucose decreased
  4. Blood glucose increased
  5. Blood pressure diastolic decreased
  6. Blood pressure systolic increased
  7. Constipation
  8. Dehydration (dryness resulting from the removal of water)
  9. Dizziness
  10. Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)

What are the common drug interactions of Trulicity and Loperamide Hydrochloride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Dehydration (dryness resulting from the removal of water)

40-49:

  1. Body mass index increased
  2. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  3. Dyslipidaemia (abnormal amount of lipids)
  4. Pneumonia

50-59:

  1. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
  2. Dizziness
  3. Infection
  4. Oedema peripheral (superficial swelling)
  5. Oropharyngeal pain
  6. Swollen tongue (swelling of tongue)

60+:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Thrombosis (formation of a blood clot inside a blood vessel)
  4. Blood glucose increased
  5. Blood pressure diastolic decreased
  6. Blood pressure systolic increased
  7. Constipation
  8. Crying
  9. Decreased appetite
  10. Dehydration (dryness resulting from the removal of water)

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 4 people, 16.00%
  2. Oesophageal Carcinoma (cancer tumour of oesophagus): 3 people, 12.00%
  3. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 12.00%
  4. Type 2 Diabetes: 2 people, 8.00%
  5. Hiv Infection: 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

Do you take Trulicity and Loperamide hydrochloride?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Trulicity and Loperamide hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Trulicity:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Loperamide hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Trulicity and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Loperamide hydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on dulaglutide and loperamide hydrochloride (the active ingredients of Trulicity and Loperamide hydrochloride, respectively), and Trulicity and Loperamide hydrochloride (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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