Trulicity and Mesalamine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trulicity (dulaglutide) and Mesalamine (mesalamine). Common drug interactions include anaemia among females and atrial fibrillation among males.

The phase IV clinical study analyzes what interactions people have when they take Trulicity and Mesalamine. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Trulicity?

Trulicity has active ingredients of dulaglutide. It is often used in weight loss. eHealthMe is studying from 77,529 Trulicity users. Check the latest studies of Trulicity.

What is Mesalamine?

Mesalamine has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 28,053 Mesalamine users. Check the latest studies of Mesalamine.



On Jul, 14, 2026

21 people who take Trulicity and Mesalamine together, and have interactions are studied.

Trulicity and Mesalamine drug interactions.

What are the common drug interactions of Trulicity and Mesalamine, by gender? *:

female:

  1. Anaemia (lack of blood)
  2. Cough
  3. Nephrolithiasis (calculi in the kidneys)
  4. Pain
  5. Pancreatitis (inflammation of pancreas)
  6. Productive cough
  7. Retching (strong involuntary effort to vomit)
  8. Upper-airway cough syndrome
  9. Abdominal pain
  10. Anaphylactic reaction (serious allergic reaction)

male:

  1. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  2. Asthenia (weakness)
  3. Death
  4. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  5. Fatigue (feeling of tiredness)
  6. Hypertension (high blood pressure)
  7. Lung disorder (lung disease)
  8. Mobility decreased (ability to move is reduced)
  9. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  10. Nasopharyngitis (inflammation of the nasopharynx)

What are the common drug interactions of Trulicity and Mesalamine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Abdominal pain
  2. Drug hypersensitivity
  3. Eructation (release of gas from the digestive tract)
  4. Flatulence (flatus expelled through the anus)
  5. Nausea (feeling of having an urge to vomit)
  6. Urticaria (rash of round, red welts on the skin that itch intensely)

50-59:

  1. Asthenia (weakness)
  2. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  3. Blood pressure decreased
  4. Dizziness
  5. Hyperhidrosis (abnormally increased sweating)
  6. Pain
  7. Pyrexia (fever)
  8. Blood pressure increased
  9. Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
  10. Maculopathy (a condition or disease of the macula, the small spot in the retina where vision is keenest)

60+:

  1. Death
  2. Sepsis (a severe blood infection that can lead to organ failure and death)
  3. Injection site reaction
  4. Mobility decreased (ability to move is reduced)
  5. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  6. Nausea (feeling of having an urge to vomit)
  7. Pneumonia
  8. Procedural pain
  9. Rectal haemorrhage (bleeding from anus)
  10. Troponin increased

What are the existing conditions these people have? *

  1. Diabetes: 11 people, 52.38%
  2. High Blood Cholesterol: 8 people, 38.10%
  3. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 23.81%
  4. Anaemia (lack of blood): 5 people, 23.81%
  5. High Blood Pressure: 4 people, 19.05%
  6. Blood Pressure Abnormal: 4 people, 19.05%
  7. Prostate Cancer: 2 people, 9.52%
  8. Nausea (feeling of having an urge to vomit): 2 people, 9.52%
  9. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

Do you take Trulicity and Mesalamine?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Trulicity and Mesalamine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Trulicity:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Mesalamine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Trulicity and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Mesalamine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on dulaglutide and mesalamine (the active ingredients of Trulicity and Mesalamine, respectively), and Trulicity and Mesalamine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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