Truvada and Ursodiol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Truvada (emtricitabine; tenofovir disoproxil fumarate) and Ursodiol (ursodiol). Common drug interactions include abdominal pain upper among females and adrenal insufficiency among males.

The phase IV clinical study analyzes what interactions people have when they take Truvada and Ursodiol. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Truvada?

Truvada has active ingredients of emtricitabine; tenofovir disoproxil fumarate. It is often used in hiv infection. eHealthMe is studying from 76,246 Truvada users. Check the latest studies of Truvada.

What is Ursodiol?

Ursodiol has active ingredients of ursodiol. It is often used in primary biliary cirrhosis. eHealthMe is studying from 19,061 Ursodiol users. Check the latest studies of Ursodiol.

On Jul, 17, 2026

22 people who take Truvada and Ursodiol together, and have interactions are studied.

What are the common drug interactions of Truvada and Ursodiol, by gender? *:

female:

Abdominal pain upper
Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
Blood pressure diastolic decreased
Cerebral disorder (brain disease)
Cholecystitis chronic (long lasting infection of gallbladder)
Deafness
Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Hodgkin's disease (cancer originating from white blood cells)
Nausea (feeling of having an urge to vomit)

male:

Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Adrenalitis (inflammation of one or both adrenal glands)
Anxiety
Aspartate aminotransferase increased
Blood lactate dehydrogenase increased
Bone density decreased
Constipation
Depression
Disease complication
Dyspepsia (indigestion)

What are the common drug interactions of Truvada and Ursodiol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal pain upper
Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
Cerebral disorder (brain disease)
Cholecystitis chronic (long lasting infection of gallbladder)
Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Nausea (feeling of having an urge to vomit)
Vertigo

30-39:

Dental caries
Periodontitis (inflammation of the tissue around the teeth)

40-49:

Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Adrenalitis (inflammation of one or both adrenal glands)
Cytomegalovirus infection
Haemolytic anaemia (anaemia due to haemolysis)
Immune reconstitution syndrome (immune recovery syndrome)
Arthropathy
Renal failure acute (rapid kidney dysfunction)
Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
Aspartate aminotransferase increased
Blood lactate dehydrogenase increased

50-59:

Abdominal pain upper
Constipation
Headache (pain in head)
Hypertension (high blood pressure)
Myalgia (muscle pain)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)

60+:

Chronic kidney disease
Anxiety
Tinnitus (a ringing in the ears)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Blood pressure diastolic decreased
Bone density decreased
Deafness
Depression
Dyspepsia (indigestion)
Emotional distress

What are the existing conditions these people have? *

Pneumocystis Jiroveci Pneumonia (fungal infection of the lungs): 3 people, 13.64%
Liver Disorder (liver diseases): 3 people, 13.64%
Fungal Infection: 3 people, 13.64%
Cytomegalovirus Infection: 3 people, 13.64%
Pain: 2 people, 9.09%
Joint Pain: 2 people, 9.09%
Itching: 2 people, 9.09%
Ischaemic Cerebral Infarction (ischemic stroke resulting from a disturbance in the blood vessels supplying blood to the brain): 2 people, 9.09%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 9.09%
Gallstones (stone formation by bile component): 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Truvada and Ursodiol?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously