Twynsta and Dexilant drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Twynsta (amlodipine besylate; telmisartan) and Dexilant (dexlansoprazole). Common drug interactions include cyanosis among females.
The phase IV clinical study analyzes what interactions people have when they take Twynsta and Dexilant. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.
What is Twynsta?
Twynsta has active ingredients of amlodipine besylate; telmisartan. It is often used in high blood pressure. eHealthMe is studying from 1,063 Twynsta users. Check the latest studies of Twynsta.
What is Dexilant?
Dexilant has active ingredients of dexlansoprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 57,103 Dexilant users. Check the latest studies of Dexilant.
13 people who take Twynsta and Dexilant together, and have interactions are studied.

What are the common drug interactions of Twynsta and Dexilant, by gender? *:
female:
- Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
- Dizziness
- Abdominal pain
- Oropharyngeal pain
- Dysphonia (speech disorder attributable to a disorder of phonation)
- Iron deficiency
- Protein urine present
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Renal injury (kidney injury)
male:
n/a
What are the common drug interactions of Twynsta and Dexilant, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Renal injury (kidney injury)
60+:
- Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
- Dizziness
- Abdominal pain
- Oropharyngeal pain
- Dysphonia (speech disorder attributable to a disorder of phonation)
- Iron deficiency
- Protein urine present
- Adverse event
- Cough
- Calcification of muscle (calcium accumulation in muscle)
What are the existing conditions these people have? *
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 46.15%
- Tuberculosis (a bacterial infection by mycobacterium tuberculosis): 2 people, 15.38%
- Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 15.38%
- Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously): 2 people, 15.38%
- Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 2 people, 15.38%
- Pain: 2 people, 15.38%
- Nausea (feeling of having an urge to vomit): 2 people, 15.38%
- Itching: 2 people, 15.38%
- Gout (uric acid crystals building up in the body): 2 people, 15.38%
- Gastrointestinal Disorder (functional problems of gastrointestinal tract): 2 people, 15.38%
* Approximation only. Some reports may have incomplete information.
Do you take Twynsta and Dexilant?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Twynsta and Dexilant:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Twynsta:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Dexilant:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Twynsta and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Dexilant and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on amlodipine besylate; telmisartan and dexlansoprazole (the active ingredients of Twynsta and Dexilant, respectively), and Twynsta and Dexilant (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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