Twynsta and Seroquel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Twynsta (amlodipine besylate; telmisartan) and Seroquel (quetiapine fumarate). Common drug interactions include neutrophil count decreased among females and dementia alzheimer's type among males.

The phase IV clinical study analyzes what interactions people have when they take Twynsta and Seroquel. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Twynsta?

Twynsta has active ingredients of amlodipine besylate; telmisartan. It is often used in high blood pressure. eHealthMe is studying from 1,063 Twynsta users. Check the latest studies of Twynsta.

What is Seroquel?

Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. eHealthMe is studying from 120,285 Seroquel users. Check the latest studies of Seroquel.



On Jul, 17, 2026

14 people who take Twynsta and Seroquel together, and have interactions are studied.

Twynsta and Seroquel drug interactions.

What are the common drug interactions of Twynsta and Seroquel, by gender? *:

female:

  1. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  2. Organic brain syndrome (decreased mental function due to a medical disease)
  3. Pericardial effusion (fluid around the heart)
  4. Perineal erythema (redness of skin in the perineal area)
  5. Pneumonia
  6. Cataract (clouding of the lens inside the eye)
  7. Dehydration (dryness resulting from the removal of water)
  8. Fall
  9. Hip arthroplasty
  10. Hypernatraemia (an abnormally high plasma concentration of sodium ions)

male:

  1. Dementia alzheimer's type (loss of mental ability with alzheimer's symptom)
  2. Chest discomfort
  3. Contusion (a type of hematoma of tissue in which capillaries)
  4. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  5. Oedema peripheral (superficial swelling)
  6. Peripheral swelling

What are the common drug interactions of Twynsta and Seroquel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Organic brain syndrome (decreased mental function due to a medical disease)
  2. Chest discomfort
  3. Contusion (a type of hematoma of tissue in which capillaries)
  4. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  5. Delirium (wild excitement)
  6. Hip arthroplasty
  7. Oedema peripheral (superficial swelling)
  8. Peripheral swelling

60+:

  1. Delirium (wild excitement)
  2. Constipation
  3. Dehydration (dryness resulting from the removal of water)
  4. Fall
  5. Hypernatraemia (an abnormally high plasma concentration of sodium ions)
  6. Pyrexia (fever)
  7. Somnolence (a state of near-sleep, a strong desire for sleep)
  8. Dementia alzheimer's type (loss of mental ability with alzheimer's symptom)
  9. Dyspepsia (indigestion)
  10. Fluid retention (an abnormal accumulation of fluid in the blood)

What are the existing conditions these people have? *

  1. Insomnia (sleeplessness): 4 people, 28.57%
  2. Depression: 4 people, 28.57%
  3. Breast Cancer: 4 people, 28.57%
  4. Pain: 4 people, 28.57%
  5. Type 2 Diabetes: 3 people, 21.43%
  6. Metastases To Bone (cancer spreads to bone): 3 people, 21.43%
  7. Diabetes: 3 people, 21.43%
  8. Delirium (wild excitement): 2 people, 14.29%
  9. Infusion Related Reaction: 2 people, 14.29%
  10. Dyspnea (difficult or laboured breathing): 2 people, 14.29%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Twynsta and Seroquel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Twynsta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Seroquel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Twynsta and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Seroquel and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on amlodipine besylate; telmisartan and quetiapine fumarate (the active ingredients of Twynsta and Seroquel, respectively), and Twynsta and Seroquel (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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