Tylenol w/ codeine no. 3 and Soliris drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tylenol w/ codeine no. 3 (acetaminophen; codeine phosphate) and Soliris (eculizumab). Common drug interactions include insomnia among females and atrial fibrillation among males.

The phase IV clinical study analyzes what interactions people have when they take Tylenol w/ codeine no. 3 and Soliris. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Tylenol w/ codeine no. 3?

Tylenol w/ codeine no. 3 has active ingredients of acetaminophen; codeine phosphate. It is often used in pain. eHealthMe is studying from 4,920 Tylenol w/ codeine no. 3 users. Check the latest studies of Tylenol w/ codeine no. 3.

What is Soliris?

Soliris has active ingredients of eculizumab. It is often used in paroxysmal nocturnal hemoglobinuria (pnh). eHealthMe is studying from 58,821 Soliris users. Check the latest studies of Soliris.

On Jul, 11, 2026

13 people who take Tylenol w/ codeine no. 3 and Soliris together, and have interactions are studied.

Tylenol w/ codeine no. 3 and Soliris drug interactions.

What are the common drug interactions of Tylenol W/ Codeine No. 3 and Soliris, by gender? *:

female:

Insomnia (sleeplessness)
Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Vomiting
Conversion disorder (neurological symptoms, such as numbness, blindness, paralysis, or fits without a definable organic cause)
Diarrhoea
Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid)
Helicobacter gastritis (inflammation of the inner lining of the stomach caused by helicobacter pylori (h. pylori) a bacterium)
Hypotension (abnormally low blood pressure)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)

male:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cellulitis (infection under the skin)
Sepsis (a severe blood infection that can lead to organ failure and death)
Urinary tract infection
Ascites (accumulation of fluid in the abdominal cavity)
Asthenia (weakness)
Budd-chiari syndrome (problem that results from blood clotting in the veins flowing out of the liver (hepatic veins))
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Laryngeal injury
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

What are the common drug interactions of Tylenol W/ Codeine No. 3 and Soliris, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Vomiting
Conversion disorder (neurological symptoms, such as numbness, blindness, paralysis, or fits without a definable organic cause)
Diarrhoea
Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid)
Headache (pain in head)
Helicobacter gastritis (inflammation of the inner lining of the stomach caused by helicobacter pylori (h. pylori) a bacterium)
Hypotension (abnormally low blood pressure)
Insomnia (sleeplessness)
Nausea (feeling of having an urge to vomit)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)

30-39:

Device related infection
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)

40-49:

Blood bilirubin increased
Disturbance in attention
Fatigue (feeling of tiredness)
Platelet count decreased
Tremor (trembling or shaking movements in one or more parts of your body)

50-59:

n/a

60+:

Drug ineffective
Dyspnoea (difficult or laboured respiration)
Sepsis (a severe blood infection that can lead to organ failure and death)
Urinary tract infection
Renal failure (kidney dysfunction)
Ascites (accumulation of fluid in the abdominal cavity)
Asthenia (weakness)
Budd-chiari syndrome (problem that results from blood clotting in the veins flowing out of the liver (hepatic veins))
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Laryngeal injury

What are the existing conditions these people have? *

Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 13 people, 100.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 15.38%
Anaemia (lack of blood): 2 people, 15.38%
Muscle Spasms (muscle contraction): 2 people, 15.38%
Iron Overload: 2 people, 15.38%
Headache (pain in head): 2 people, 15.38%
Thyroid Cancer: 1 person, 7.69%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 1 person, 7.69%
Back Pain: 1 person, 7.69%
Birth Control: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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