Tylenol w/ codeine and Librium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tylenol w/ codeine (acetaminophen; codeine phosphate) and Librium (chlordiazepoxide hydrochloride). Common drug interactions include monocyte count increased among females and cerebrovascular accident among males.

The phase IV clinical study analyzes what interactions people have when they take Tylenol w/ codeine and Librium. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Tylenol w/ codeine?

Tylenol w/ codeine has active ingredients of acetaminophen; codeine phosphate. It is often used in pain. eHealthMe is studying from 8,107 Tylenol w/ codeine users. Check the latest studies of Tylenol w/ codeine.

What is Librium?

Librium has active ingredients of chlordiazepoxide hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 2,490 Librium users. Check the latest studies of Librium.

On Jul, 25, 2026

35 people who take Tylenol w/ codeine and Librium together, and have interactions are studied.

Tylenol w/ codeine and Librium drug interactions.

What are the common drug interactions of Tylenol W/ Codeine and Librium, by gender? *:

female:

Monocyte count increased
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Neutrophil count increased (excess than normal number of neutrophil a type of blood cell)
Pain in extremity
Platelet count decreased
Pulmonary congestion (congestion in the lungs)
Somnolence (a state of near-sleep, a strong desire for sleep)
Suicidal ideation
Thirst
Acne cystic (skin problems that cause pimples)

male:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Agitation (state of anxiety or nervous excitement)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Colitis pseudomembranous (antibiotic-associated diarrhoea)
Coma (state of unconsciousness lasting more than six hours)
Delirium (wild excitement)
Depressed level of consciousness
Depression
Drug dependence
Drug ineffective

What are the common drug interactions of Tylenol W/ Codeine and Librium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Drug addiction
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)

30-39:

Arthralgia (joint pain)
Asthma
Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Depressed level of consciousness
Depression
Drug abuser
Drug dependence
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Dysarthria (speech disorder)

40-49:

Blood lactate dehydrogenase increased
Depression
Drug dependence
Hallucination (an experience involving the perception of something not present)
Hepatic function abnormal
Hostility
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Suicide attempt
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Aspartate aminotransferase increased

50-59:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Drug ineffective
Fatigue (feeling of tiredness)
Insomnia (sleeplessness)
Papilloedema (optic disc swelling)
Photosensitivity reaction
Retinal disorder (disease of retina)
Vision blurred
Visual field defect

60+:

Depression
Homicidal ideation (thoughts about human killing another human)
Adverse drug reaction
Anaemia postoperative
Blood pressure increased
Blood urea decreased
Dysstasia (difficulty in standing)
Extrasystoles
Lymphocyte count decreased
Monocyte count increased

What are the existing conditions these people have? *

Depression: 16 people, 45.71%
Back Pain: 14 people, 40.00%
Quit Smoking: 12 people, 34.29%
Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 6 people, 17.14%
Abdominal Discomfort: 6 people, 17.14%
High Blood Pressure: 5 people, 14.29%
Gastric Disorder (disease of stomach): 4 people, 11.43%
Osteoporosis (bones weak and more likely to break): 3 people, 8.57%
Sleep Disorder: 2 people, 5.71%
High Blood Cholesterol: 2 people, 5.71%

* Approximation only. Some reports may have incomplete information.

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