Tyr and Adderall drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tyr (tyrosine) and Adderall (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate). Common drug interactions include fibromyalgia among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Tyr and Adderall. It is created by eHealthMe based on reports of 69 people who take the same drugs from the FDA, and is updated regularly.

What is Tyr?

Tyr has active ingredients of tyrosine. eHealthMe is studying from 840 Tyr users. Check the latest studies of Tyr.

What is Adderall?

Adderall has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 64,226 Adderall users. Check the latest studies of Adderall.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

69 people who take Tyr and Adderall together, and have interactions are studied.

What are the common drug interactions of Tyr and Adderall, by gender? *:

female:

Fibromyalgia (a long-term condition which causes pain all over the body)
Muscle spasms (muscle contraction)
Peritonsillar abscess (painful pus filled inflammation of the tonsils and surrounding tissues)
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Sluggishness (lacking alertness)
Viral infection
Wisdom teeth removal
Abdominal distension
Abnormal sleep-related event
Abortion spontaneous (naturally occurring miscarriage)

male:

Anxiety
Fatigue (feeling of tiredness)
Activities of daily living impaired
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Arthralgia (joint pain)
Asthenia (weakness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blood cholesterol increased
Blood oestrogen decreased
Burning sensation

What are the common drug interactions of Tyr and Adderall, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Fibromyalgia (a long-term condition which causes pain all over the body)
Peritonsillar abscess (painful pus filled inflammation of the tonsils and surrounding tissues)
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Suicidal ideation
Wisdom teeth removal

20-29:

Fatigue (feeling of tiredness)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Abnormal behaviour
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Arthralgia (joint pain)
Asthenia (weakness)
Blood cholesterol increased
Blood oestrogen decreased
Burning sensation
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)

30-39:

Fatigue (feeling of tiredness)
Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)
Dizziness
Depressed mood
Drug ineffective
Feeling hot
Insomnia (sleeplessness)
Oropharyngeal pain
Apathy

40-49:

Abdominal distension
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Asthenia (weakness)
Bipolar disorder (mood disorder)
Brain injury
Cat scratch disease (bacterial infection by cat scratch)
Cerebral disorder (brain disease)
Chest discomfort

50-59:

Drug ineffective
Cough
Disturbance in attention
Dyspepsia (indigestion)
Fatigue (feeling of tiredness)
Gastric disorder (disease of stomach)
Type 2 diabetes mellitus
Wrist surgery

60+:

n/a

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 48 people, 69.57%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 31 people, 44.93%
Drowsiness: 6 people, 8.70%
Depression: 6 people, 8.70%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 4 people, 5.80%

* Approximation only. Some reports may have incomplete information.

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