Tyvaso and Daliresp drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tyvaso (treprostinil sodium) and Daliresp (roflumilast). Common drug interactions include nausea among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Tyvaso and Daliresp. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Tyvaso?

Tyvaso has active ingredients of treprostinil sodium. eHealthMe is studying from 37,941 Tyvaso users. Check the latest studies of Tyvaso.

What is Daliresp?

Daliresp has active ingredients of roflumilast. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 4,722 Daliresp users. Check the latest studies of Daliresp.

On Aug, 13, 2026

17 people who take Tyvaso and Daliresp together, and have interactions are studied.

What are the common drug interactions of Tyvaso and Daliresp, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Dizziness
Headache (pain in head)
Choking (mechanical obstruction of the flow of air from the environment into the lungs)
Dyspnoea (difficult or laboured respiration)
Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)
Retching (strong involuntary effort to vomit)
Acute respiratory failure
Anxiety
Asthenia (weakness)

male:

Dyspnoea (difficult or laboured respiration)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Contusion (a type of hematoma of tissue in which capillaries)
Diarrhoea
Discomfort
Dizziness
Epistaxis (bleed from the nose)
Eye irritation
Eye pruritus (eye itching)
Fatigue (feeling of tiredness)

What are the common drug interactions of Tyvaso and Daliresp, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Acute respiratory failure
Anxiety
Asthenia (weakness)
Balance disorder
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Chest pain
Choking (mechanical obstruction of the flow of air from the environment into the lungs)
Crying
Depression

60+:

Nausea (feeling of having an urge to vomit)
Dizziness
Epistaxis (bleed from the nose)
Eye irritation
Eye pruritus (eye itching)
Fatigue (feeling of tiredness)
Haemoglobin decreased
Headache (pain in head)
Hyperkalaemia (damage to or disease of the kidney)
Hypotension (abnormally low blood pressure)

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 16 people, 94.12%

* Approximation only. Some reports may have incomplete information.

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