Zoloft and Persantine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zoloft (sertraline hydrochloride) and Persantine (dipyridamole). Common drug interactions include gait disturbance among females and agitation among males.

The phase IV clinical study analyzes what interactions people have when they take Zoloft and Persantine. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Zoloft?

Zoloft has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 138,798 Zoloft users. Check the latest studies of Zoloft.

What is Persantine?

Persantine has active ingredients of dipyridamole. eHealthMe is studying from 2,427 Persantine users. Check the latest studies of Persantine.

On Aug, 13, 2026

33 people who take Zoloft and Persantine together, and have interactions are studied.

Zoloft and Persantine drug interactions.

What are the common drug interactions of Zoloft and Persantine, by gender? *:

female:

Gait disturbance
Haemorrhagic anaemia (anaemia due to excessive bleeding)
Hypersomnia (excessive daytime sleepiness (eds))
Influenza
Insomnia (sleeplessness)
International normalised ratio increased
Intestinal stoma complication
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Nerve injury
Overdose

male:

Agitation (state of anxiety or nervous excitement)
Cardiac failure
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Blood carbon dioxide decreased
Blood creatine phosphokinase increased
Blood creatinine increased
Blood ph decreased
Blood urea increased
Cardiomegaly (increased size of heart than normal)
Chest discomfort

What are the common drug interactions of Zoloft and Persantine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Enteritis haemorrhagic (acute gi disorder with sudden vomiting and bloody diarrhoea)
Hypokalaemia (low potassium)
Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract)
Nausea (feeling of having an urge to vomit)
Vomiting
Abdominal adhesions (inflammation of abdomen)
Dehydration (dryness resulting from the removal of water)
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Enterocolitis haemorrhagic (bleeding and inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon)
Intestinal stoma complication

60+:

Hypotension (abnormally low blood pressure)
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Abdominal adhesions (inflammation of abdomen)
Abdominal distension
Abdominal pain
Acute respiratory distress syndrome
Agitation (state of anxiety or nervous excitement)
Cardiac failure
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chest pain

What are the existing conditions these people have? *

Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 6.06%

* Approximation only. Some reports may have incomplete information.

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