Tyvaso and Metronidazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tyvaso (treprostinil sodium) and Metronidazole (metronidazole). Common drug interactions include epistaxis among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Tyvaso and Metronidazole. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Tyvaso?

Tyvaso has active ingredients of treprostinil sodium. eHealthMe is studying from 37,941 Tyvaso users. Check the latest studies of Tyvaso.

What is Metronidazole?

Metronidazole has active ingredients of metronidazole. It is often used in vaginitis bacterial. eHealthMe is studying from 59,578 Metronidazole users. Check the latest studies of Metronidazole.



On Jul, 18, 2026

35 people who take Tyvaso and Metronidazole together, and have interactions are studied.

Tyvaso and Metronidazole drug interactions.

What are the common drug interactions of Tyvaso and Metronidazole, by gender? *:

female:

  1. Epistaxis (bleed from the nose)
  2. Eructation (release of gas from the digestive tract)
  3. Face oedema (swelling of face)
  4. Full blood count decreased
  5. Ocular hyperaemia (an abnormally large amount of blood in eye)
  6. Peripheral swelling
  7. Pharyngitis bacterial (inflammation of the pharynx, causing a sore throat due to bacterial infection)
  8. Productive cough
  9. Somnolence (a state of near-sleep, a strong desire for sleep)
  10. Upper-airway cough syndrome

male:

  1. Diarrhoea
  2. Constipation
  3. Nausea (feeling of having an urge to vomit)
  4. Oedema (fluid collection in tissue)
  5. Pain
  6. Respiratory tract congestion (blockage on respiratory system)
  7. Retching (strong involuntary effort to vomit)
  8. Sepsis (a severe blood infection that can lead to organ failure and death)
  9. Weight decreased
  10. Fatigue (feeling of tiredness)

What are the common drug interactions of Tyvaso and Metronidazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
  2. Osteomyelitis (infection of bone)
  3. Oxygen saturation decreased
  4. Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)

40-49:

  1. Contusion (a type of hematoma of tissue in which capillaries)
  2. Diarrhoea
  3. Abdominal pain
  4. Asthenia (weakness)
  5. Blood disorder
  6. Chest pain
  7. Cough
  8. Decreased appetite
  9. Dizziness
  10. Dyspnoea (difficult or laboured respiration)

50-59:

  1. Chest pain
  2. Dizziness
  3. Dyspnoea (difficult or laboured respiration)
  4. Fluid overload (too much fluid in the blood)
  5. Hospitalisation
  6. Hypoxia (low oxygen in tissues)
  7. Pain in jaw
  8. Palpitations (feelings or sensations that your heart is pounding or racing)
  9. Peripheral swelling
  10. Pleuritic pain

60+:

  1. Diarrhoea
  2. Abdominal discomfort
  3. Hearing disability
  4. Hepatic pain (pain in liver)
  5. Sinusitis (inflammation of sinus)
  6. Full blood count decreased
  7. Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
  8. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  9. Lymphadenopathy (disease or enlargement of lymph nodes)
  10. Productive cough

What are the existing conditions these people have? *

  1. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 26 people, 74.29%
  2. Oral Candidiasis (fungal infection of mouth): 7 people, 20.00%
  3. Pharyngitis Streptococcal (inflammation of the pharynx caused by infection from. streptococcus): 5 people, 14.29%
  4. Multiple Allergies (allergy to multiple agents): 5 people, 14.29%
  5. Infection: 5 people, 14.29%
  6. Pulmonary Hypertension (increase in blood pressure in the lung artery): 3 people, 8.57%
  7. Idiopathic Pulmonary Fibrosis (chronic lung disease): 2 people, 5.71%

* Approximation only. Some reports may have incomplete information.

Do you take Tyvaso and Metronidazole?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Tyvaso and Metronidazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tyvaso:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Metronidazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tyvaso and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Metronidazole and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on treprostinil sodium and metronidazole (the active ingredients of Tyvaso and Metronidazole, respectively), and Tyvaso and Metronidazole (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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