Uloric and Daliresp drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Uloric (febuxostat) and Daliresp (roflumilast). Common drug interactions include chronic kidney disease among females and anxiety among males.
The phase IV clinical study analyzes what interactions people have when they take Uloric and Daliresp. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.
What is Uloric?
Uloric has active ingredients of febuxostat. It is often used in gout. eHealthMe is studying from 8,067 Uloric users. Check the latest studies of Uloric.
What is Daliresp?
Daliresp has active ingredients of roflumilast. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 4,722 Daliresp users. Check the latest studies of Daliresp.
17 people who take Uloric and Daliresp together, and have interactions are studied.

What are the common drug interactions of Uloric and Daliresp, by gender? *:
female:
- Chronic kidney disease
- Arthralgia (joint pain)
- Balance disorder
- Coccydynia (pain in the coccyx or tailbone area)
- Fall
- Renal failure (kidney dysfunction)
male:
- Anxiety
- Chronic kidney disease
- Emotional distress
- Fear
- Hip arthroplasty
- Mood swings (an extreme or rapid change in mood)
- Multiple fractures
- Nephropathy (damage to or disease of a kidney)
- Pain
- Psychiatric symptom
What are the common drug interactions of Uloric and Daliresp, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Asthenopia (eyestrain-tiredness of the eyes caused by prolonged close work by a person with an uncorrected vision problem)
- Back pain
- Contusion (a type of hematoma of tissue in which capillaries)
- Dental discomfort
- Depression
- Stasis dermatitis (skin inflammation caused by blood pooling in the veins in your legs)
- Therapeutic response unexpected
- Anxiety
- Disturbance in attention
- Fear
60+:
- Chronic kidney disease
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Renal impairment (severely reduced kidney function)
- Decreased appetite
- Fall
- Nephrogenic anaemia (anaemia due to kidney disease)
- Osteonecrosis (death of bone)
- Abdominal distension
- Arthralgia (joint pain)
- Asthenia (weakness)
What are the existing conditions these people have? *
- High Blood Cholesterol: 6 people, 35.29%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 35.29%
- Fluid Retention (an abnormal accumulation of fluid in the blood): 6 people, 35.29%
- Diabetes: 5 people, 29.41%
- Pain: 5 people, 29.41%
- Neuralgia (pain in one or more nerves): 4 people, 23.53%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 17.65%
- Hiv Infection: 3 people, 17.65%
- Glaucoma (increased fluid pressure in the eye with vision loss): 3 people, 17.65%
- Irritable Bowel Syndrome: 3 people, 17.65%
* Approximation only. Some reports may have incomplete information.
Do you take Uloric and Daliresp?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Uloric and Daliresp:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Uloric:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Daliresp:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Uloric and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Daliresp and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on febuxostat and roflumilast (the active ingredients of Uloric and Daliresp, respectively), and Uloric and Daliresp (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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