Uloric and Zaditor drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Uloric (febuxostat) and Zaditor (ketotifen fumarate). Common drug interactions include death among females and depression among males.
The phase IV clinical study analyzes what interactions people have when they take Uloric and Zaditor. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.
What is Uloric?
Uloric has active ingredients of febuxostat. It is often used in gout. eHealthMe is studying from 8,067 Uloric users. Check the latest studies of Uloric.
What is Zaditor?
Zaditor has active ingredients of ketotifen fumarate. It is often used in eye allergy. eHealthMe is studying from 4,448 Zaditor users. Check the latest studies of Zaditor.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
16 people who take Uloric and Zaditor together, and have interactions are studied.

What are the common drug interactions of Uloric and Zaditor, by gender? *:
female:
- Death
male:
- Depression
- Hospitalisation
- Weight increased
- Diarrhoea
- Insomnia (sleeplessness)
- Cough
- Hypersensitivity
- Oral discomfort (pain or irritation in mouth)
- Schizophrenia (a mental disorder characterized by a breakdown of thought processes)
- Suicidal ideation
What are the common drug interactions of Uloric and Zaditor, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Diarrhoea
- Insomnia (sleeplessness)
30-39:
- Ankle fracture
- Confusional state
- Encephalopathy (functioning of the brain is affected by some agent or condition)
- Lung disorder (lung disease)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Therapeutic response unexpected
40-49:
n/a
50-59:
n/a
60+:
n/a
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 14 people, 87.50%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 11 people, 68.75%
- Primary Myelofibrosis (primary disorder of the bone marrow): 1 person, 6.25%
- Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 1 person, 6.25%
- Joint Pain: 1 person, 6.25%
- Bone Pain: 1 person, 6.25%
* Approximation only. Some reports may have incomplete information.
Do you take Uloric and Zaditor?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Uloric and Zaditor:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Uloric:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Zaditor:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Uloric and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Zaditor and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on febuxostat and ketotifen fumarate (the active ingredients of Uloric and Zaditor, respectively), and Uloric and Zaditor (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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