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Ultram and Trovan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ultram (tramadol hydrochloride) and Trovan (trovafloxacin mesylate). Common drug interactions include vomiting among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Ultram and Trovan. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Ultram?

Ultram has active ingredients of tramadol hydrochloride. It is often used in pain. eHealthMe is studying from 28,425 Ultram users. Check the latest studies of Ultram.

What is Trovan?

Trovan has active ingredients of trovafloxacin mesylate. eHealthMe is studying from 2,227 Trovan users. Check the latest studies of Trovan.

On Aug, 09, 2026

13 people who take Ultram and Trovan together, and have interactions are studied.

Ultram and Trovan drug interactions.

What are the common drug interactions of Ultram and Trovan, by gender? *:

female:

  1. Vomiting
  2. Anaemia (lack of blood)
  3. Dehydration (dryness resulting from the removal of water)
  4. Nausea (feeling of having an urge to vomit)
  5. Pyrexia (fever)
  6. Headache (pain in head)
  7. Sepsis (a severe blood infection that can lead to organ failure and death)
  8. Application site reaction
  9. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
  10. Drug addiction

male:

  1. Arthralgia (joint pain)
  2. Accident
  3. Blood pressure increased
  4. Breath sounds
  5. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  6. Cardiac disorder
  7. Cardiac failure congestive
  8. Cardioactive drug level increased
  9. Cardiomegaly (increased size of heart than normal)
  10. Cardiomyopathy (weakening of the heart muscle)

What are the common drug interactions of Ultram and Trovan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Arthralgia (joint pain)
  2. Myalgia (muscle pain)

50-59:

  1. Headache (pain in head)
  2. Syncope (loss of consciousness with an inability to maintain postural tone)
  3. Ventricular arrhythmia (problem with the rate or rhythm of the heartbeat)
  4. Vomiting
  5. Anaemia (lack of blood)
  6. Dehydration (dryness resulting from the removal of water)
  7. Nausea (feeling of having an urge to vomit)
  8. Pyrexia (fever)
  9. Sepsis (a severe blood infection that can lead to organ failure and death)
  10. Bacterial infection

60+:

  1. Headache (pain in head)
  2. Pruritus (severe itching of the skin)

* Approximation only. Some reports may have incomplete information.

Do you take Ultram and Trovan?

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- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ultram and Trovan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ultram:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Trovan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ultram and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Trovan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on tramadol hydrochloride and trovafloxacin mesylate (the active ingredients of Ultram and Trovan, respectively), and Ultram and Trovan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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