Uniphyl and Avapro drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Uniphyl (theophylline) and Avapro (irbesartan). Common drug interactions include emotional disorder among females and bronchitis among males.
The phase IV clinical study analyzes what interactions people have when they take Uniphyl and Avapro. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.
What is Uniphyl?
Uniphyl has active ingredients of theophylline. eHealthMe is studying from 3,086 Uniphyl users. Check the latest studies of Uniphyl.
What is Avapro?
Avapro has active ingredients of irbesartan. It is often used in high blood pressure. eHealthMe is studying from 19,840 Avapro users. Check the latest studies of Avapro.
17 people who take Uniphyl and Avapro together, and have interactions are studied.

What are the common drug interactions of Uniphyl and Avapro, by gender? *:
female:
- Emotional disorder
- Fatigue (feeling of tiredness)
- Injection site erythema (redness at injection site)
- Injection site warmth
- Muscle spasms (muscle contraction)
- Palpitations (feelings or sensations that your heart is pounding or racing)
- Pruritus (severe itching of the skin)
- Urticaria (rash of round, red welts on the skin that itch intensely)
- Asthma
- Fall
male:
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Renal failure (kidney dysfunction)
- Dehydration (dryness resulting from the removal of water)
- Delusional disorder, unspecified type
- Depression
- Diarrhoea
- Drug dependence
- Drug tolerance increased
- Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
- Dysphonia (speech disorder attributable to a disorder of phonation)
What are the common drug interactions of Uniphyl and Avapro, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
n/a
60+:
- Fatigue (feeling of tiredness)
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Anaemia (lack of blood)
- Anxiety
- Chest discomfort
- Cor pulmonale (enlargement of the right ventricle of the heart)
- Dehydration (dryness resulting from the removal of water)
- Delusional disorder, unspecified type
- Depression
- Diarrhoea
What are the existing conditions these people have? *
- Asthma: 6 people, 35.29%
- Pain: 4 people, 23.53%
- Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 11.76%
- Osteoporosis (bones weak and more likely to break): 2 people, 11.76%
- Sinus Disorder (disease of sinus): 1 person, 5.88%
- Secretion Discharge: 1 person, 5.88%
- Prostatic Disorder: 1 person, 5.88%
- Gastric Disorder (disease of stomach): 1 person, 5.88%
- Eye Disorder: 1 person, 5.88%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 5.88%
* Approximation only. Some reports may have incomplete information.
Do you take Uniphyl and Avapro?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Uniphyl and Avapro:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Uniphyl:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Avapro:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Uniphyl and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Avapro and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Korang-Yeboah M, Rahman Z, Shah D, Mohammad A, Wu S, Siddiqui A, Khan MA, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International journal of pharmaceutics, 2016 Feb .
- Dhaval MK, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International Journal of Pharmaceutics, 2016 Jan .
- Korang-Yeboah M, Rahman Z, Shah D, Mohammad A, Wu S, Siddiqui A, Khan MA, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International journal of pharmaceutics, 2016 Feb .
- Dhaval MK, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International Journal of Pharmaceutics, 2016 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on theophylline and irbesartan (the active ingredients of Uniphyl and Avapro, respectively), and Uniphyl and Avapro (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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