Uniphyl and Protonix drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Uniphyl (theophylline) and Protonix (pantoprazole sodium). Common drug interactions include renal failure among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Uniphyl and Protonix. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Uniphyl?

Uniphyl has active ingredients of theophylline. eHealthMe is studying from 3,086 Uniphyl users. Check the latest studies of Uniphyl.

What is Protonix?

Protonix has active ingredients of pantoprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 132,658 Protonix users. Check the latest studies of Protonix.

On Jul, 14, 2026

32 people who take Uniphyl and Protonix together, and have interactions are studied.

What are the common drug interactions of Uniphyl and Protonix, by gender? *:

female:

Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Acute respiratory failure
Death
Status asthmaticus (a asthma attack not responds to regular medicines)
Nausea (feeling of having an urge to vomit)
Cough
Eye pain
Migraine (headache)
Muscle spasms (muscle contraction)

male:

Fatigue (feeling of tiredness)
Abdominal distension
Abdominal discomfort
Abdominal pain upper
Anxiety
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Chest discomfort
Cor pulmonale (enlargement of the right ventricle of the heart)
Cough
Dehydration (dryness resulting from the removal of water)

What are the common drug interactions of Uniphyl and Protonix, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Acute respiratory failure
Asthma
Status asthmaticus (a asthma attack not responds to regular medicines)

30-39:

n/a

40-49:

Diarrhoea
Headache (pain in head)
Pyrexia (fever)
Abdominal distension
Adverse drug reaction
Adverse event
Anaemia (lack of blood)
Arthralgia (joint pain)
Asthenia (weakness)
Blood glucose increased

50-59:

Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Eye pain
Fatigue (feeling of tiredness)
Headache (pain in head)
Injection site erythema (redness at injection site)
Injection site pain
Injection site rash
Migraine (headache)
Nausea (feeling of having an urge to vomit)
Pruritus (severe itching of the skin)

60+:

Renal failure (kidney dysfunction)
Cough
Chest discomfort
Cor pulmonale (enlargement of the right ventricle of the heart)
Dehydration (dryness resulting from the removal of water)
Delusional disorder, unspecified type
Depression
Diarrhoea
Drug dependence
Drug tolerance increased

What are the existing conditions these people have? *

Pain: 6 people, 18.75%
Asthma: 5 people, 15.62%
Stress And Anxiety: 2 people, 6.25%
Osteoporosis (bones weak and more likely to break): 2 people, 6.25%
Nausea (feeling of having an urge to vomit): 2 people, 6.25%
Depression: 2 people, 6.25%
Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 2 people, 6.25%
Constipation: 2 people, 6.25%
Breast Cancer: 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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